Evidence map›Paper›PMID 42352495›Full record

ArticleCancers2026

Clinical and Sociodemographic Determinants of Treatment Selection in Prostate Cancer: A Population-Based Study in the United States (2004-2022).

Manas Pustake, Atharva Railkar, Stevenson Ongsyping, Swarada Joshi, Oboseh Ogedegbe, Mohammad Arfat Ganiyani, Sumit Gaur, Jesus Gomez, Rohan Garje

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Manas PustakeDepartment of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.ORCID 0000-0002-3566-0389
Atharva RailkarDepartment of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.ORCID 0009-0006-6819-9206
Stevenson OngsypingDepartment of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
Swarada JoshiDepartment of Internal Medicine, NRI Institute of Medical Sciences, Visakhapatnam 531162, Andhra Pradesh, India.
Oboseh OgedegbeDepartment of Internal Medicine, Trinity Health Ann Arbor Hospital, Ypsilanti, MI 48197, USA.ORCID 0009-0000-7213-2166
Mohammad Arfat GaniyaniDepartment of Medical Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0002-6202-0117
Sumit GaurDepartment of Hematology and Oncology, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.ORCID 0000-0002-9958-9470
Jesus GomezDepartment of Hematology and Oncology, University Medical Center of El Paso, El Paso, TX 79905, USA.
Rohan GarjeDepartment of Medical Oncology, Miami Cancer Institute, Baptist Health South Florida, Miami, FL 33176, USA.ORCID 0000-0002-7244-5602

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProstate cancer remains one of the most prevalent malignancies and a leading cause of cancer-related mortality among men in the United States, with more than 300,000 new cases diagnosed annually. As the burden of disease continues to rise, ensuring equitable access to effective treatment remains a critical public health priority. Unequal access to definitive surgical management among disadvantaged populations may contribute to preventable morbidity and mortality. Radical prostatectomy is a cornerstone treatment for localized disease; however, its utilization has evolved over time in response to changing screening guidelines, technological advancements, and shifting treatment paradigms. Despite these developments, disparities in access to surgical management persist.

methodsUsing the Surveillance, Epidemiology, and End Results database, we conducted a retrospective cohort study evaluating factors associated with radical prostatectomy utilization among 917,194 men with localized or regional prostate cancer diagnosed between 2004 and 2022. Multivariable logistic regression assessed demographic, socioeconomic, and clinical predictors of surgical treatment.

resultsOverall, 33.5% of patients underwent radical prostatectomy. Increasing age was strongly associated with lower odds of surgery (OR 0.904 per year, 95% CI 0.903-0.904,

conclusionsThese findings demonstrate that treatment selection in prostate cancer is influenced not only by disease characteristics but also by sociodemographic factors, highlighting persistent disparities in access to definitive surgical care and the need for targeted interventions to improve equity in treatment delivery.

Indexed as

healthcare disparitieshealth equitypopulation-based studyprostate cancerprostate cancer managementradical prostatectomySEER databasesociodemographic factorssurgical utilizationtreatment disparities

Identifiers

PMID42352495
PMCPMC13297215

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