Evidence map›Paper›PMID 42352430›Full record

ArticleCancers2026

The Imipridone ONC206 Inhibits Tumor Growth and Improves Survival in Patient-Derived Xenograft Models of Uveal Melanoma.

Mir Mustafa Ali, Md Alauddin, Iqbal Mahmud, Aron Joon, Aalim B Momin, Jacob R Cortez, Huiqin Chen, Lin Tan, Waikin Chan, Rachel William Anantha and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Mir Mustafa AliDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.ORCID 0009-0008-4165-7216
Md AlauddinDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.
Iqbal MahmudDepartment of Bioinformatics & Comp Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Aron JoonDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0003-2615-2179
Aalim B MominDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.
Jacob R CortezDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.
Huiqin ChenDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0003-2477-5436
Lin TanDepartment of Metabolomics Core Facility, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Waikin ChanDepartment of Metabolomics Core Facility, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Rachel William AnanthaDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.
Danielle L StolleyDepartment of Hematopoietic Biology & Malignancies, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Diana ShamsutdinovaDepartment of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.ORCID 0000-0003-1057-1731
Kurt EvansDepartment of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Funda Merric-BernstamDepartment of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Meenhard HerlynMelanoma Research Center, Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Monzy ThomasMelanoma Research Center, Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Yeqing ChenMelanoma Research Center, Molecular and Cellular Oncogenesis Program, The Wistar Institute, Philadelphia, PA 19104, USA.
Michael A DaviesDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.ORCID 0000-0002-0977-0912
Chandrani ChattopadhyayDepartment of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 362, Houston, TX 77030, USA.

Funding

Anne and Don Fizer Foundation NADr. Miriam and Sheldon G. Adelson Medical Research Foundation NAMulva Family Foundation NA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

autophagyimipridoneslipidomicsliver metastasisoxidative phosphorylationPDXuveal melanoma (UM)

Identifiers

PMID42352430
PMCPMC13296402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.