Evidence map›Paper›PMID 42352372›Full record

ArticleBiomolecules2026

Exosomal circ_0050688 Shapes a Chemoresistant Microenvironment by Driving Spatial Resistance Spreading in Glioblastoma via the MDM2 Pathway.

Qiang Li, Jianglong Xu, Yuhao Zhang, Junbing Qian, Diana Bee-Lan Ong, Kein Seong Mun, Yiping Tang, Xiuchao Geng, Kean Chang Phang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qiang LiSchool of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
Jianglong XuDepartment of Neurosurgery, Affiliated Hospital of Hebei University, Baoding 071000, Hebei, China.
Yuhao ZhangDepartment of Neurosurgery, Zhejiang Provincial People's Hospital, Affiliated to Hangzhou Medical College, Hangzhou 310014, Zhejiang, China.
Junbing QianSchool of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
Diana Bee-Lan OngDepartment of Pathology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Kein Seong MunDepartment of Pathology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.
Yiping TangDepartment of Psychosomatic, Taizhou Second People's Hospital, Affiliated to School of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.
Xiuchao GengSchool of Medicine, Taizhou University, Taizhou 318000, Zhejiang, China.ORCID 0000-0002-3386-1443
Kean Chang PhangDepartment of Pathology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur 50603, Malaysia.ORCID 0000-0002-6843-9613

Funding

Zhejiang Provincial Natural Science Foundation LTGD24H160007, LMS25C040004, LTGY24C060003
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Brain NeoplasmsDrug Resistance, NeoplasmExosomesGlioblastomaProto-Oncogene Proteins c-mdm2RNA, CircularTumor MicroenvironmentAnimalsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMaleMiceMice, NudeMDM2 protein, humanProto-Oncogene Proteins c-mdm2RNA, CircularTemozolomideacquired chemoresistancecirc_0050688exosomesglioblastomaMDM2

Identifiers

PMID42352372
PMCPMC13296696

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.