ArticleBiomolecules2026
Bone Marrow-Derived Mesenchymal Stem Cells Alleviate Cutaneous Leishmaniasis by Promoting M2 Macrophage Polarization and Skin Tissue Repair in a Murine Model.
Shirui Bai, Tao Lin, Haoxia Li, Bo Han, John P Kastelic, Tao Zhang, Hao Shi, Gang Liu, Yipeng Jin
Abstract read
In one paragraphArticle in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
9 authors.
Shirui BaiState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Tao LinState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Haoxia LiState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Bo HanState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0002-4798-7725 Tao ZhangState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Hao ShiState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Gang LiuState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-1541-5180 Yipeng JinState Key Laboratory of Veterinary Public Health and Safety, Department of Clinical Veterinary Medicine, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0001-5244-8358 Funding
China Agricultural University 1051-2225002Ministry of Agriculture and Rural Affairs NY2502180325Ministry of Science and Technology of the People's Republic of China 2024YFD1800200
6 · The paper itselfAbstract
Cutaneous leishmaniasis (CL) is the most common clinical form of leishmaniasis, characterized by persistent skin ulcers and nodules. Standard chemotherapeutic agents have substantial toxicity and do nothing to repair the damaged tissue, an unmet need that motivates the search for adjunctive strategies. Mesenchymal stem cells (MSCs) can modulate macrophage activity and support tissue regeneration, yet their role in CL has received limited attention. In this study, we tested whether bone marrow-derived MSCs (BM-MSCs) could attenuate
Indexed as
Leishmaniasis, CutaneousMacrophagesMesenchymal Stem CellsMesenchymal Stem Cell TransplantationSkinAnimalsArginaseBone Marrow CellsCoculture TechniquesDisease Models, AnimalFemaleInterleukin-10Leishmania mexicanaMiceMice, Inbred BALB CNitric Oxide Synthase Type IIArginaseInterleukin-10Nitric Oxide Synthase Type IIhost-directed therapyLeishmania mexicanalesion pathologymacrophage immunomodulationskin wound healing
Identifiers
PMID42352363
PMCPMC13297385
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