Evidence map›Paper›PMID 42352327›Full record

ArticleBiomolecules2026

A Pyrone Glucoside from

Jamila Aminu, Amina Jega Yusuf, Bor-Jang Hwang, Sonia Kamran, Nasiru Abdullahi, Adamu Jibril Alhassan, John Obadipe, Valerie Odero-Marah, Hajjagana Hamza, Abdullahi Ibrahim Uba and 2 more

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jamila AminuDepartment of Chemistry, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.
Amina Jega YusufDepartment of Chemistry, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.
Bor-Jang HwangDepartment of Biology, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.ORCID 0009-0001-4455-9266
Sonia KamranDepartment of Chemistry, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.ORCID 0009-0005-7818-1045
Nasiru AbdullahiDepartment of Biochemistry, Bayero University, P.M.B. 3011, Gwarzo Road, Kano, Nigeria.
Adamu Jibril AlhassanDepartment of Biochemistry, Bayero University, P.M.B. 3011, Gwarzo Road, Kano, Nigeria.
John ObadipeDepartment of Biology, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.
Valerie Odero-MarahDepartment of Biology, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.ORCID 0000-0001-7525-4652
Hajjagana HamzaDepartment of Biochemistry, Gombe State University, P.M.B. 127, Tudun Wada, Gombe, Gombe State, Nigeria.ORCID 0000-0001-8804-2309
Abdullahi Ibrahim UbaDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, İstinye University, 34396 Istanbul, Türkiye.ORCID 0000-0002-0853-108X
James WachiraDepartment of Biology, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.ORCID 0000-0002-6689-3265
Jiangnan PengDepartment of Chemistry, Morgan State University, 1700 E. Cold Spring Lane, Baltimore, MD 21251, USA.ORCID 0000-0001-5785-737X

Funding

NIGMS NIH HHS 5UL1GM118973NIMHD NIH HHS 5U54MD013376
6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) is an aggressive subtype lacking effective targeted therapies, highlighting the need for new anticancer agents. Natural products remain a valuable source of bioactive compounds with diverse mechanisms of action. In this study, a pyrone glucoside, 7-hydroxymaltol-3-

Indexed as

ApoptosisGlucosidesPoly (ADP-Ribose) Polymerase-1Proto-Oncogene Proteins c-aktPyronesTriple Negative Breast NeoplasmsCaspase 7Cell Line, TumorFemaleHumansMolecular Docking SimulationPlant ExtractsCaspase 7GlucosidesPARP1 protein, humanPlant ExtractsPoly (ADP-Ribose) Polymerase-1Proto-Oncogene Proteins c-aktPyronescytotoxic activityMaerua angolensisMDA-MB-468 cellspyrone glucosidetriple-negative breast cancer

Identifiers

PMID42352327
PMCPMC13297593

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.