Evidence map›Paper›PMID 42352324›Full record

ArticleBiomolecules2026

Optotransduction Pathway, Exploring Connections with Inflammation.

Alessandro Ravoni, Veronica Paparozzi, Tiziana Guarnieri, Cecilia Sanzini, Luigi Manni, Christine Nardini

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro RavoniConsiglio Nazionale delle Ricerche, Istituto per le Applicazioni del Calcolo "Mauro Picone", 00185 Roma, Italy.ORCID 0000-0003-0228-1806
Veronica PaparozziConsiglio Nazionale delle Ricerche, Istituto per le Applicazioni del Calcolo "Mauro Picone", 00185 Roma, Italy.ORCID 0009-0000-2961-1559
Tiziana GuarnieriConsiglio Nazionale delle Ricerche, Istituto per le Applicazioni del Calcolo "Mauro Picone", 00185 Roma, Italy.ORCID 0000-0002-5069-5010
Cecilia SanziniConsiglio Nazionale delle Ricerche, Istituto per le Applicazioni del Calcolo "Mauro Picone", 00185 Roma, Italy.
Luigi ManniConsiglio Nazionale delle Ricerche, Istituto di Farmacologia Traslazionale, 00185 Roma, Italy.ORCID 0000-0001-7844-6836
Christine NardiniConsiglio Nazionale delle Ricerche, Istituto per le Applicazioni del Calcolo "Mauro Picone", 00185 Roma, Italy.ORCID 0000-0001-7601-321X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of cells to translate optical radiation into biochemical signals, i.e., optotransduction, plays an important role in the life sciences, including the development of emerging therapeutic strategies, with a relevant influence on inflammation. However, a systemic understanding of the molecular pathways underlying the transduction of these physical stimuli is still lacking. In this work, we present a molecular map of optotransduction reconstructed from the literature and provide its representation as pathway, using the standard Systems Biology Markup Language. This representation enables network-based analyses and allows us to explore the differential effect of stimuli wavelengths and, for the first time, the systematic overlap with other forms of physical transduction, namely mechanotransduction.

Indexed as

InflammationMechanotransduction, CellularAnimalsHumansSignal TransductionSystems Biologyinflammationnetwork biologyoptotransductionpathwayphotobiomodulationsystems biology markup language

Identifiers

PMID42352324
PMCPMC13296732

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.