Evidence map›Paper›PMID 42352299›Full record

ReviewBiomolecules2026

Regulatory Roles of Adiponectin in Animal Reproduction: Molecular Insights from the Hypothalamic-Pituitary-Gonadal Axis.

Yixiang Tian, Xing Wu, Lujie Zhang, Yujie Gong, Xiangtao Kang, Yadong Tian, Yulong Guo

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yixiang TianCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Xing WuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Lujie ZhangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Yujie GongCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Xiangtao KangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0002-9628-7135
Yadong TianCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.
Yulong GuoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0003-0006-4672

Funding

National Natural Science Foundation of China NO.32472899the Key Research and Development Special Projects of Henan Province 241111113600the Special Fund for Henan Agricuture Research System HARS-22-18-S
6 · The paper itself

Abstract

Adiponectin, an adipocyte-derived adipokine, plays a key regulatory role in physiological processes such as energy balance, glucose metabolism, and fatty acid oxidation. Evidence from animal studies indicates that adiponectin is involved in the regulation of reproductive performance by mediating molecular crosstalk between energy metabolism and the reproductive system. As the core regulatory center for animal reproduction, the hypothalamic-pituitary-gonadal (HPG) axis exhibits a close link between its functional state and the body's energy homeostasis. This review systematically summarizes the expression patterns and molecular mechanisms of adiponectin and its receptors at different levels of the animal HPG axis. It provides a theoretical basis for future research and applications of adiponectin in animal reproduction.

Indexed as

AdiponectinHypothalamic-Pituitary-Gonadal AxisHypothalamo-Hypophyseal SystemReproductionAnimalsEnergy MetabolismHumansReceptors, AdiponectinAdiponectinReceptors, AdiponectinadiponectinAdipoR1/2hypothalamic–pituitary–gonadal axisregulationreproduction

Identifiers

PMID42352299
PMCPMC13296796

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.