Evidence map›Paper›PMID 42352071›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Tetrahydrocurcumin Attenuates NaIO

Tzu-Chun Chen, Thuy-Lan-Thi Vo, Shang-Chun Tsou, Hui-Min David Wang, Inga Wang, Chen-Ju Chuang, Hui-Wen Lin, Yuan-Yen Chang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tzu-Chun ChenInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Thuy-Lan-Thi VoDepartment of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Shang-Chun TsouInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Hui-Min David WangGraduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung 402, Taiwan.ORCID 0000-0002-4692-4917
Inga WangRehabilitation Sciences & Technology, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA.ORCID 0000-0002-4553-7130
Chen-Ju ChuangEmergency Department, St. Martin De Porres Hospital, Chiayi 600, Taiwan.
Hui-Wen LinInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.
Yuan-Yen ChangDepartment of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung 402, Taiwan.ORCID 0000-0001-6395-4280

Funding

National Science and Technology Council MOST 111-2320-B-040 -006 -MY3
6 · The paper itself

Abstract

Oxidative stress is a major contributor to the development of age-related macular degeneration (AMD), and excessive oxidative stress can induce retinal pigment epithelium (RPE) dysfunction, apoptosis, and retinal degeneration. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase 2 (NOX2) is a major enzymatic source of reactive oxygen species (ROS); however, its mechanistic role in sodium iodate (NaIO

Indexed as

age-related macular degeneration (AMD)apoptosisNaIO3NOX2 and MEK/ERK signaling pathwaytetrahydrocurcumin (THC)

Identifiers

PMID42352071
PMCPMC13295685

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.