Evidence map›Paper›PMID 42352047›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Glutathione Transferase as a Potential First-Tier Biomarker of Environmental Pollution in Workers and Residents of Umbria Region, Italy.

Sara Notari, Fiorella Faienza, Giovanna Tranfo, Anna Maria Caccuri, Giorgio Ricci, Giorgia Gambardella

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sara NotariDepartment of Chemical Sciences and Technologies, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.
Fiorella FaienzaDepartment of Chemical Sciences and Technologies, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0001-6148-0333
Giovanna TranfoDepartment of Occupational Medicine, Epidemiology, Occupational and Environmental Hygiene, INAIL Research, Via Fontana Candida 1, Monte Porzio Catone, 00078 Rome, Italy.ORCID 0000-0001-8973-6046
Anna Maria CaccuriDepartment of Chemical Sciences and Technologies, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.ORCID 0000-0002-3756-4163
Giorgio RicciDepartment of Chemical Sciences and Technologies, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.
Giorgia GambardellaDepartment of Chemical Sciences and Technologies, University of Rome 'Tor Vergata', Via della Ricerca Scientifica 1, 00133 Rome, Italy.

Funding

Istituto Nazionale per l'Assicurazione Contro gli Infortuni sul Lavoro Grant BRIC 2022 ID 52University of Tor Vergata E83C25000500005
6 · The paper itself

Abstract

Erythrocyte glutathione transferase (e-GST) and oxidized human serum albumin (HSAox) were used as biomarkers to assess the environmental health of a foundry and a ceramics factory located in the Umbria region (Italy). While HSAox level indicates that no relevant oxidative stress is present in workers of either company, a distinct overexpression of e-GST, also present in non-workers residents, suggests exposure to broad environmental stressors that may be attributed to common sources. A more careful analysis of different job sectors and the effect of filtering facepieces indicates that the workers exposed to solvents show the highest e-GST expression, while different pollutants (possibly dust and/or metal fumes) seem to be present in other areas of the foundry as well as in external areas. In the ceramic company, the high e-GST activity reveals the presence of other contaminants which can be efficiently blocked by filtering facepieces and gloves together. Intriguingly, a cohort of monks (

Indexed as

environmental pollutionerythrocyte glutathione transferasehuman biomonitoringoccupational exposure monitoringoxidative stress

Identifiers

PMID42352047
PMCPMC13295966

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.