Evidence map›Paper›PMID 42351983›Full record

ReviewAntioxidants (Basel, Switzerland)2026

Potential of Native Brazilian Fruits in Modulating Oxidative Stress and Inflammation: A Focused Review.

Maria Carolina Zsigovics Alfino, Geni Rodrigues Sampaio, Adriano Costa de Camargo, Elizabeth Aparecida Ferraz da Silva Torres

Abstract readReview
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Maria Carolina Zsigovics AlfinoDepartment of Nutrition, School of Public Health, University of Sao Paulo, 715 Doutor Arnaldo Ave, Sao Paulo 01246-904, Brazil.ORCID 0009-0009-3780-8672
Geni Rodrigues SampaioDepartment of Nutrition, School of Public Health, University of Sao Paulo, 715 Doutor Arnaldo Ave, Sao Paulo 01246-904, Brazil.ORCID 0000-0002-7763-4664
Adriano Costa de CamargoInstituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Santiago 7500910, Chile.ORCID 0000-0001-9404-1193
Elizabeth Aparecida Ferraz da Silva TorresDepartment of Nutrition, School of Public Health, University of Sao Paulo, 715 Doutor Arnaldo Ave, Sao Paulo 01246-904, Brazil.ORCID 0000-0002-1012-1418

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic non-communicable diseases are closely linked to low-grade inflammation and oxidative stress. Native Brazilian fruits, rich in bioactive compounds such as polyphenols and carotenoids, have recognized antioxidant, anti-inflammatory, and neuroprotective properties. Mechanisms of action included inhibition of NF-κB signaling, downregulation of pro-inflammatory cytokines, modulation of oxidative biomarkers, and improvement of metabolic parameters. Several studies demonstrate protective effects against insulin resistance, hepatic steatosis, cardiovascular alterations, and neuroinflammation, alongside modulation of gut microbiota. Most evidence is from animal or cell models, with scarce clinical trials, limiting translational applicability. Overall, native Brazilian fruits represent promising dietary sources of bioactive compounds that may contribute to the modulation of oxidative stress and chronic inflammation. Challenges include variability in phytochemical content due to species, maturity, processing, a lack of standardized extraction and dosage protocols, and limited bioavailability data. Although preclinical findings are robust, further controlled human trials are necessary to confirm their efficacy and clarify their role in the clinical management of inflammatory and neurodegenerative diseases.

Indexed as

dietinflammationnative Brazilian fruitsphenolic compoundspublic health

Identifiers

PMID42351983
PMCPMC13482957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.