Evidence map›Paper›PMID 42351907›Full record

ArticleBioengineering (Basel, Switzerland)2026

Comparative Histological Evaluation of Collagen Matrix Architectures for Soft Tissue Augmentation in the Oral Cavity: A Preclinical Canine Model.

Hana Shah, Nicholas J Iglesias, Sara E Munkwitz, Blaire V Slavin, Zachary M Stauber, Quinn T Ehlen, Vasudev Vivekanand Nayak, Seth R Thaller, Lukasz Witek, Paulo G Coelho

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hana ShahUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0009-0005-2469-2587
Nicholas J IglesiasDeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0002-5935-997X
Sara E MunkwitzUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0009-0009-7107-3235
Blaire V SlavinUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Zachary M StauberUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Quinn T EhlenUniversity of Miami Miller School of Medicine, Miami, FL 33136, USA.
Vasudev Vivekanand NayakDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-2739-0339
Seth R ThallerDeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Lukasz WitekBiomaterials and Regenerative Biology Division, NYU College of Dentistry, New York, NY 10010, USA.ORCID 0000-0003-1458-6527
Paulo G CoelhoDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

Funding

Regenity Biosciences N/A
6 · The paper itself

Abstract

Intraoral soft-tissue defects are traditionally managed with autogenous connective tissue grafts, though donor site morbidity has driven interest in xenogeneic collagen matrices as alternatives. However, the impact of matrix architecture on soft-tissue integration remains poorly understood. This study compared soft-tissue responses to a sheet-form collagen matrix (ShCM) and a spongy collagen matrix (SpCM) placed beneath full-thickness flaps in a beagle mandibular defect model. Standardized bilateral defects were created in 23 skeletally mature female beagles. Defects were then assigned to serve as the negative control (sham) or were treated with porcine collagen matrix in (i) sheet form (ShCM) (Regenity Biosciences, Oakland, NJ, USA), or (ii) porous/spongy form (SpCM) (Fibro-Gide

Indexed as

collagen matrixintraoral augmentationsoft tissue augmentationxenograft

Identifiers

PMID42351907
PMCPMC13295686

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.