ArticleBioengineering (Basel, Switzerland)2026
Calibrated Deep-Learning Risk Indexing and Latent Behavioural Profiling for Occupational Mental-Health Risk Assessment.
Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Occupational mental-health risk in knowledge-work settings is an important public-health and psychosocial-support concern because workload demands, career insecurity, limited mentoring, uneven institutional support and barriers to care can increase psychological risk, including in early-career academic environments. Workplace well-being assessments rely on aggregate survey summaries or conventional prediction models, limiting calibration, interpretability, subgroup evaluation and transfer validation. This study develops a computational-intelligence framework for public mental-health decision support using heterogeneous workplace survey data with early-career academics treated as a motivating knowledge-work context rather than as the direct empirical cohort. The proposed approach combines attention-based tabular learning, variational autoencoder latent profiling, stacked ensemble prediction, probability calibration, feature attribution, perturbation analysis, fairness assessment and cross-dataset adaptation. Calibrated probabilities are converted into a transparent 0-100 risk index to support preventive outreach, psychosocial-support planning and resource-allocation decisions. The model is compared with baselines, including logistic regression, support vector machine, random forest, XGBoost, LightGBM, CatBoost, TabNet, FT-Transformer, NODE and DCN. Results show strong held-out performance with AUC = 0.885, average precision = 0.872, F1 = 0.808, Brier score = 0.145 and expected calibration error = 0.022, outperforming tested baselines. Five-fold robustness analysis produced a conservative mean test AUC of 0.809±0.044, indicating moderate partition sensitivity. Key predictors include work interference, perceived stress, care access and support variables. Latent profiling identifies two behavioural subgroups with distinct risk patterns. After feature harmonization, target-domain adaptation and recalibration, external evaluation on an occupational burnout dataset achieves AUC = 0.941 and average precision = 0.936, supporting calibrated, interpretable and subgroup-aware decision support under dataset shift.
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