Evidence map›Paper›PMID 42351788›Full record

ReviewBiomedicines2026

Allergen Immunotherapy and Possible Clinical Remission: Toward a Disease-Modifying Paradigm in Allergic Disorders.

Fabiana Furci, Remo Poto, Corrado Pelaia, Gilda Varricchi, Chiara Lupia, Vincenzo Patella, Gianenrico Senna, Girolamo Pelaia, Giorgio Walter Canonica

Abstract readReview
In one paragraph

Review in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabiana FurciAllergy Section, Provincial Healthcare Unit, 89900 Vibo Valentia, Italy.ORCID 0000-0002-5062-3076
Remo PotoDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.ORCID 0000-0002-4723-0167
Corrado PelaiaDepartment of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0002-4236-7367
Gilda VarricchiDepartment of Translational Medical Sciences, University of Naples Federico II, 80131 Naples, Italy.
Chiara LupiaDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0009-0004-8786-3489
Vincenzo PatellaDepartment of Internal Medicine ASL Salerno, 'Santa Maria Della Speranza' Hospital, 84091 Salerno, Italy.
Gianenrico SennaDepartment of Medicine, University of Verona, 37134 Verona, Italy.ORCID 0000-0003-4172-3216
Girolamo PelaiaDepartment of Health Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.ORCID 0000-0001-9288-8913
Giorgio Walter CanonicaDepartment of Biomedical Science, Humanitas University, 20072 Pieve Emanuele, Italy.ORCID 0000-0001-8467-2557

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergen immunotherapy (AIT) represents the only disease-modifying treatment currently available for IgE-mediated allergic diseases. Traditionally employed to alleviate symptoms and reduce pharmacological dependence, AIT is now being reconsidered within a broader and more ambitious therapeutic framework: the induction of long-term clinical remission. In the field of allergic diseases, the concept of disease control has recently been integrated with that of clinical remission. This review discusses the evolving concept of remission in allergic disorders, particularly allergic rhinitis and allergic asthma, in patients treated with AIT. Starting from the definition of clinical remission, this review aims to analyze the evidence supporting this concept and explore potential tools for clinical application in allergic patients treated with AIT, the only causal therapy.

Indexed as

AITallergen immunotherapyallergic rhinitisasthmaremission

Identifiers

PMID42351788
PMCPMC13297453

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.