Evidence map›Paper›PMID 42351613›Full record

ReviewBiomedicines2026

Pharmacotherapeutic Options in Drug-Resistant Bipolar Depression: From Molecular Mechanisms to Rational Polypharmacotherapy.

Dominik Jucha, Michał Klimas, Dominika Wiśniewska, Martyna Winiarska, Mateusz Szczupak, Jacek Kobak, Sabina Krupa-Nurcek

Abstract readReview
In one paragraph

Review in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dominik JuchaFaculty of Medicine, Collegium Medicum, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0009-0004-3219-4740
Michał KlimasFaculty of Medicine, Collegium Medicum, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0009-0003-0010-3835
Dominika WiśniewskaFaculty of Medicine, Collegium Medicum, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0009-0007-6459-3844
Martyna WiniarskaFaculty of Medicine, Collegium Medicum, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0009-0007-2387-8958
Mateusz SzczupakDepartment of Anaesthesiology and Intensive Therapy of the Nicolaus Copernicus Hospital in Gdańsk, 80-808 Gdansk, Poland.ORCID 0009-0009-3094-2385
Jacek KobakDepartment of Otolaryngology, Faculty of Medicine, Medical University of Gdańsk, 80-210 Gdansk, Poland.
Sabina Krupa-NurcekDepartment of Surgery, Faculty of Medicine, Collegium Medicum, University of Rzeszów, 35-310 Rzeszów, Poland.ORCID 0000-0002-3002-3153

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

augmentationbipolar disorderdrug-resistant bipolar depressionketaminenormothymic drugspolypharmacotherapypramipexolesecond-generation antipsychoticsSSRIsTRBD

Identifiers

PMID42351613
PMCPMC13296849

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.