Evidence map›Paper›PMID 42351525›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Whole-Body Dynamic Positron Emission and Computed Tomography (WBD-PET/CT): Latest Developments, Challenges and Opportunities.

Anastasios Vatalis, Dimitra Tsivaka, Varvara Valotassiou, Emmanouil Panagiotidis, Panagiotis Georgoulias, Nicolas A Karakatsanis, Ioannis Tsougos

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Anastasios VatalisMedical Physics Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0009-0003-6517-6103
Dimitra TsivakaMedical Physics Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-4584-0236
Varvara ValotassiouDepartment of Nuclear Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0001-8439-6708
Emmanouil PanagiotidisDepartment of Nuclear Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-8501-3905
Panagiotis GeorgouliasDepartment of Nuclear Medicine, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.
Nicolas A KarakatsanisDepartment of Radiology, Weill Cornell Medical College, New York, NY 10021, USA.ORCID 0000-0001-7326-3053
Ioannis TsougosMedical Physics Department, Faculty of Medicine, School of Health Sciences, University of Thessaly, 41500 Larissa, Greece.ORCID 0000-0002-5204-5273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole-body dynamic positron emission tomography/computed tomography (WBD-PET/CT) has transformed medical imaging, enabling the fusion between (i) detailed anatomical maps of the human body and (ii) quantitative multi-parametric functional maps of specific biochemical and physiological processes across the human body beyond the semi-quantitative limitations of static PET/CT imaging. Latest developments in systems hardware, particularly with the introduction of long-axial-field-of-view (LAFOV) and Time-of-Flight (TOF) PET scanners and low-dose CT scanners, and in data analysis, primarily with direct parametric PET image reconstruction and Artificial Intelligence, offer unprecedented opportunities towards the wide clinical adoption of the superior quantitative accuracy and precision of WBD-PET/CT imaging overcoming current challenges, such as data acquisition complexity and long scan durations. This review aims to summarize the latest developments, current challenges, and emerging opportunities in WBD-PET/CT, emphasizing its potential to broaden the diagnostic and theranostic role of PET/CT in clinical practice.

Indexed as

digital PET/CTdynamic PET/CTradio-pharmacokineticstheranostics

Identifiers

PMID42351525
PMCPMC13298687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.