Evidence map›Paper›PMID 42351498›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Application of Artificial Intelligence in Breast Ultrasound Diagnosis.

Jian Zhang, André Pfob, Eva Reisig, Lie Cai

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jian ZhangFaculty of Medicine, Freiburg University, 79085 Freiburg, Germany.
André PfobDepartment of Breast Unit, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Eva ReisigDepartment of Breast Unit, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Lie CaiDepartment of Breast Unit, Heidelberg University Hospital, 69120 Heidelberg, Germany.ORCID 0009-0002-3899-3346

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) is reshaping ultrasound diagnosis by converting operator-dependent grayscale, Doppler, elastography, contrast-enhanced, automated-volume, and video data into reproducible decision support. In breast ultrasound, the most mature evidence involves benign-malignant lesion classification, BI-RADS risk stratification, reduction in unnecessary biopsy in selected low-risk lesions, assistance for less experienced readers, automated breast volume scanning, video-based assessment, axillary staging, and prediction of biologic markers such as molecular subtype, HER2 status, Ki-67 expression, lymphovascular invasion, and nodal metastasis. AI does not replace sonographers, radiologists, pathologists, or clinical judgment; rather, it can standardize feature extraction, prompt second-reader review, quantify uncertainty, and integrate imaging with clinical context. This review summarizes current clinical applications of AI in ultrasound diagnosis, which has a strong recent multicenter evidence base. It also discusses implementation requirements, including standardized acquisition, external validation, calibration, imaging-pathology concordance, workflow integration, data security, and equity across scanners and patient populations.

Indexed as

artificial intelligenceautomated breast ultrasoundaxillary lymph nodeBI-RADSbreast ultrasoundcomputer-aided diagnosisdeep learningelastographyradiomicsultrasound diagnosis

Identifiers

PMID42351498
PMCPMC13298338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.