Evidence map›Paper›PMID 42351484›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Emerging Pathways to Non-Invasive Diagnosis in Endometriosis: Integrating Machine Learning, Deep Learning and Multi-Omics Biomarkers.

Daniel Markov, Jasmin Gurung, Usman Khalid, Kristian Bechev, Vladimir Aleksiev, Galabin Markov, Elena Poryazova

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel MarkovDepartment of General and Clinical Pathology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-4015-3514
Jasmin GurungFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0007-7996-4433
Usman KhalidFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0004-9425-2539
Kristian BechevDepartment of General and Clinical Pathology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0007-1460-3522
Vladimir AleksievDepartment of Thoracic Surgery, UMHAT "Kaspela", 4002 Plovdiv, Bulgaria.ORCID 0009-0004-7860-6632
Galabin MarkovFaculty of Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0009-0006-9169-5945
Elena PoryazovaDepartment of General and Clinical Pathology, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis is a chronic, debilitating condition affecting approximately 10-15% of reproductive-aged women and it is often associated with significant diagnostic delays due to its heterogeneity and unreliable non-invasive tests. Artificial intelligence (AI) offers innovative methods for improving endometriosis diagnosis, prognosis and research via advanced pattern recognition and data analysis capabilities. The integration of AI in diagnostic workflow has the potential to improve efficiency, accuracy, and patient outcomes. This review summarises current developments of AI-including machine learning, deep learning, and natural language processing-in the diagnostic workflow of endometriosis. It analyses different fields of diagnostics ranging from AI-assisted imaging in detection of pouch of Douglas to multi-omics biomarkers assisting the clinical decision process. AI can enhance accuracy, reducing diagnostic delays and supporting personalised treatment planning. However, there are multiple limitations, such as small datasets, overfitting, and lack of external validation and variability. Further research and evaluation are required before it can be implemented into healthcare systems. AI holds promise as a non-invasive, scalable adjunct to current diagnostics, potentially reducing the economic and personal burden endometriosis carries.

Indexed as

artificial intelligencedeep learning imagingendometriosismachine learningmulti-omics biomarkersnon-invasive diagnosis

Identifiers

PMID42351484
PMCPMC13298153

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.