Evidence map›Paper›PMID 42351412›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Hypoxia Associated Integration of Epigenetic, Metabolic, and Immune Biomarkers in Blood and Urine for Early Colorectal Cancer Detection: A Multimarker Panel.

Christopher Birigwa, Bing Qu, Yongqing Tong, Teng Zuo, Wenzheng Yuan, Qingbo Wang, Wei Song, Weiwei Wan, Jing Xiong, Jianfei Luo and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Christopher BirigwaDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0009-0002-4425-6342
Bing QuDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Yongqing TongDepartment of Clinical Laboratory, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Teng ZuoDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Wenzheng YuanDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Qingbo WangDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Wei SongDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0003-4576-1949
Weiwei WanDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jing XiongSchool of Medicine, Wuhan University of Science and Technology, Wuhan 430065, China.
Jianfei LuoDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0003-1788-9734
Qiang TongDepartment of Gastrointestinal Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.ORCID 0000-0002-0179-9681

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

circulating cell-free DNA (cfDNA)colorectal cancerdiagnostic accuracyinflammatory biomarkers (NLRliquid biopsyLMR)methylated SEPT9 (mSEPT9)multimarker diagnostic panelN1,N12-diacetylspermine (DiAcSpm)non-invasive cancer detectionPLR

Identifiers

PMID42351412
PMCPMC13298955

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.