Evidence map›Paper›PMID 42351170›Full record

ArticleJournal of nanobiotechnology2026

Dual reinforcement of PEKK composites with hydroxyapatite and silicon nitride nanowires for enhanced mechanical, tribological, antibacterial, and osteogenic performance.

Yuewen Xue, Lina Sun, Qinghua Tan, Tongtong Cui, Wanzhu Hao, Xia Luo, Ningyi Xian, Xijing He, Leilei Zhang, Ting Zhang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuewen XueDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China.
Lina SunState Key Laboratory of Solidification Processing, Shaanxi Key Laboratory of Fiber Reinforced Light Composite Materials, Northwestern Polytechnical University, Xi'an, 710072, P. R. China.
Qinghua TanDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China.
Tongtong CuiInstitute for Technical Chemistry and Polymer Chemistry (ITCP), Karlsruhe Institute of Technology (KIT), Engesserstraße 18, 76131, Karlsruhe, Germany.
Wanzhu HaoDepartment of Rehabilitation, Beijing Rehabilitation Hospital of Capital Medical University, Beijing, 100043, P. R. China.
Xia LuoDepartment of Medical Imaging, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China.
Ningyi XianDepartment of Dermatology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China.
Xijing HeDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China. xijing_h@vip.tom.com.
Leilei ZhangState Key Laboratory of Solidification Processing, Shaanxi Key Laboratory of Fiber Reinforced Light Composite Materials, Northwestern Polytechnical University, Xi'an, 710072, P. R. China. zhangleilei@nwpu.edu.cn.
Ting ZhangDepartment of Orthopedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710000, P. R. China. xjtumed1@163.com.

Funding

"111" project of China B08040Investigator Initiated Trial (IIT) Clinical Research Foundation of the Second Affiliated Hospital of Xi'an Jiaotong University IIT001National Natural Science Foundation of China 51872232National Natural Science Foundation of China 82372417the Joint Funds of the National Natural Science Foundation of China No. U21B2067the Key R&D Program of Shaanxi Province 2021ZDLGY14-04the Key Scientific and Technological Innovation Research Team of Shaanxi Province 2022TD-31the Research Fund of the State Key Laboratory of Solidification Processing (NWPU) No. 136-QP-2015
6 · The paper itself

Abstract

Polyetherketoneketone (PEKK) has attracted interest for load-bearing orthopedic implants due to its favorable elastic modulus and radiolucency; however, its biological inertness and weak interfacial bonding limit its clinical application. Here, we developed a dual-reinforced PEKK composite by incorporating hydroxyapatite (HA) particles and silicon nitride (SN) nanowires to improve its mechanical, tribological, antibacterial, and osteogenic properties. The ternary PEKK/HA/SN composite (PSH) exhibited tensile, compressive, and flexural strengths of 112.23, 241.36, and 201.48 MPa, increased from 23.04, 92.34, and 60.23 MPa for pure PEKK, respectively. Under dry sliding conditions, PSH showed a friction coefficient of 0.34 and a wear rate of 0.69 × 10

Indexed as

Anti-Bacterial AgentsDurapatiteKetonesNanowiresOsteogenesisSilicon CompoundsAnimalsBenzophenonesBiocompatible MaterialsEscherichia coliMaterials TestingMiceOsteoblastsPolyether CompoundsPolymersStaphylococcus aureusAnti-Bacterial AgentsBenzophenonesBiocompatible MaterialsDurapatiteKetonesPolyether CompoundspolyetheretherketonePolymersSilicon Compoundssilicon nitrideHydroxyapatiteOsseointegrationPEKK compositesSilicon nitride nanowiresTribological stability

Identifiers

PMID42351170
PMCPMC13560440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.