Evidence map›Paper›PMID 42351150›Full record

ArticleBMC oral health2026

Digitally-driven optimization of intraoral water jet parameters for plaque removal: a personalized 3D-guided orthogonal study.

Suli Guo, Li Gao, Hu Chen, Yaopeng Zhang, Feng Wu, Sukun Tian, Xu Zhang, Yuchun Sun

Abstract read
In one paragraph

Article in BMC oral health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Suli Guo *Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.
Li Gao *Department of Periodontology, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, 100081, PR China.
Hu ChenCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.
Yaopeng ZhangCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China.
Feng WuDepartment of Prosthodontics, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, PR China.
Sukun TianCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China. sukhum169@hotmail.com.
Xu ZhangCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China. zhangxulove@bjmu.edu.cn.
Yuchun SunCenter of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices & NHC Key Laboratory of Digital Stomatology & Beijing Key Laboratory of Digital Stomatology & Key Laboratory of Digital Stomatology, Chinese Academy of Medical Sciences, No.22, Zhongguancun South Avenue, Haidian District, Beijing, 100081, PR China. kqsyc@bjmu.edu.cn.

Funding

Beijing Life Science Academy (BLSA) 2024300CD0230Joint Program on Health Science & Technology Innovation of Hainan Province WSJK2025ZD215National Key Research and Development Program of China 2024YFB4607800National Natural Science Foundations of China 52035001National Natural Science Foundations of China 82572435Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2023-PT320-09
6 · The paper itself

Abstract

backgroundEffective plaque biofilm control is essential for preventing caries and periodontal diseases. Although oral irrigation devices (water flossers) are widely used as an adjunct to toothbrushing, the specific influence of their core engineering parameters-nozzle diameter, working distance, and water pressure-on plaque removal efficacy remains poorly characterized in vivo, leaving both clinical recommendations and device design without robust evidence. This study aimed to systematically optimize these parameters using a digitally guided orthogonal experimental design.

methodsA three-factor, three-level orthogonal design (L9 array) was employed, testing nozzle diameters of 0.4, 0.5, 0.6 mm, working distances of 1.0, 1.5, 2.0 mm, and water pressures of 70, 80, 90 psi. For each of the nine parameter sets, personalized titanium alloy guides were digitally designed using intraoral scan data and fabricated via 3D printing to ensure precise application on six test teeth per participant (n = 12). The guide featured a retention device and a water outlet assembly with calibrated nozzles. Plaque was disclosed before and after a standardized 30-second irrigation. Plaque removal rates within the defined Target Zone (T-Zone) were calculated using a 3D quantitative analysis method based on intraoral scans.

resultsIntuitive analysis and analysis of variance (ANOVA) of the orthogonal data revealed the influence rank: water pressure > working distance > nozzle diameter. The optimal parameter combination was determined to be a 0.5 mm nozzle diameter, 1.5 mm working distance, and 90 psi water pressure. Validation with this combination achieved a plaque removal rate of 90.21% ± 2.34% in the T-Zone.

conclusionsThis study identifies water pressure as a primary determinant of water jet efficacy, with optimal results achieved at specific intermediate settings for nozzle diameter and working distance. The methodology combining personalized 3D-printed guides with orthogonal design presents a practical digital framework for the in-vivo optimization of dental therapeutic parameters.

Indexed as

Dental PlaquePrinting, Three-DimensionalTherapeutic IrrigationEquipment DesignHumansToothbrushingWaterWater3D printingDental plaqueIntraoral scannerOrthogonal designParameter optimizationWater jet

Identifiers

PMID42351150
PMCPMC13555871

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.