Evidence map›Paper›PMID 42351099›Full record

SynthesisBMC complementary medicine and therapies2026

Traditional medicinal knowledge and diversity of medicinal plants in Benin: a systematic review (2014-2023).

Edna Hounsa, Inés Reigada, Phénix Assogba, Eric Agbodjento, Fréjus Ohouko, Boris Legba, Hornel Koudokpon, Jean Robert Klotoe, Christine Ouinsavi, Víctor López and 2 more

Abstract readSystematic Review
In one paragraph

Synthesis in BMC complementary medicine and therapies, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Edna HounsaResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0002-1774-1695
Inés ReigadaDivision of Pharmaceutical Biosciences, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0003-4799-2011
Phénix AssogbaResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0002-8866-6442
Eric AgbodjentoResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0001-7578-6595
Fréjus OhoukoResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0002-8008-6486
Boris LegbaResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0003-2622-4363
Hornel KoudokponResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0002-2688-8795
Jean Robert KlotoeResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin.ORCID http://orcid.org/0000-0002-5470-9061
Christine OuinsaviForestry Studies and Research Laboratory, University of Parakou, BP 123, Parakou, Benin.ORCID http://orcid.org/0000-0002-2596-3896
Víctor LópezDepartment of Pharmacy, Faculty of Health Sciences, Universidad San Jorge, Zaragoza, Spain.ORCID http://orcid.org/0000-0001-6969-1055
Leena HanskiDivision of Pharmaceutical Biosciences, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.ORCID http://orcid.org/0000-0002-3121-8542
Victorien DougnonResearch Unit in Applied Microbiology and Pharmacology of Natural Substances, Research Laboratory in Applied Biology, Polytechnic School of Abomey-Calavi, University of Abomey-Calavi, Abomey-Calavi, 01 BP 2009, Benin. victorien.dougnon@gmail.com.ORCID http://orcid.org/0000-0001-9047-7299

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe richness of flora and traditional medical knowledge in the West African country Benin translate into the integral role of medicinal plants in local healthcare. This study explored the current status of traditional medicine research in Benin by evaluating data from ethnopharmacological and ethnobotanical surveys carried out between 2014 and 2023 and identifying knowledge gaps within the sustainable use of plant-based remedies.

methodsThe Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol was used to guide the execution of the review. A total of 129 studies identified in scientific databases were analysed. The top 20 cited plant species were subjected to a comprehensive literature review to evaluate the experimental evidence to support the reported traditional uses.

resultsA total of 765 plant species belonging to 141 botanical families were cited in the included studies to treat various animal and human diseases, including infectious diseases, digestive disorders and metabolic diseases. Severe gaps in the documentation of plant collection practices, preparation stability, and preservation techniques were observed. Khaya senegalensis A.Juss. (41 citing studies), Parkia biglobosa (Jacq.) R.Br. ex G. Don (37 citing studies) and Ocimum gratissimum L. (33 citing studies) were the most frequently cited plants. Comparison of the scientific literature on the 20 most cited plant species revealed a lack of experimental evidence, even for the most frequent traditional uses.

conclusionThis study illustrated the wide spectrum of plant species applied in Beninese traditional medicine and the critical lack of experimental evidence for their traditional applications and the conservation of medicinal preparations. These findings underscore the need for sustainable harvesting practices, community-based conservation measures, and evidence-based use of plant resources to preserve biodiversity and support long-term availability. This calls for a national database, quality standards, and better integration of traditional medicine into modern healthcare.

Indexed as

Medicine, African TraditionalPhytotherapyPlants, MedicinalAnimalsBeninEthnobotanyEthnopharmacologyHumansBeninBiodiversityEvidence-based phytomedicineHuman diseaseMedicinal plantVeterinary medicine

Identifiers

PMID42351099
PMCPMC13556067

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.