Evidence map›Paper›PMID 42350871›Full record

ArticleEuropean journal of pediatrics2026

Ventilatory efficiency during high-frequency oscillatory ventilation with volume guarantee in preterm infants.

Kamal Ali, Mesaed Alsenani, Saad Alshareedah, Faisal Alamer, Piero Alberti, Abdulaziz Homedi, Saif Alsaif, Ibrahim Ali, Theodore Dassios, Anne Greenough

Abstract read
In one paragraph

Article in European journal of pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kamal AliNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Mesaed AlsenaniNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Saad AlshareedahNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Faisal AlamerNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Piero AlbertiNeonatal Intensive Care Centre, King's College Hospital, 4th Floor, Golden Jubilee Wing, Denmark Hill, London, SE5 9RS, UK.
Abdulaziz HomediNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Saif AlsaifNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Ibrahim AliNeonatal Intensive Care Department, King Abdulaziz Medical City, Riyadh, Saudi Arabia.
Theodore DassiosNeonatal Intensive Care Centre, King's College Hospital, 4th Floor, Golden Jubilee Wing, Denmark Hill, London, SE5 9RS, UK.
Anne GreenoughNeonatal Intensive Care Centre, King's College Hospital, 4th Floor, Golden Jubilee Wing, Denmark Hill, London, SE5 9RS, UK. anne.greenough@kcl.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to evaluate the relationship between ventilator-derived carbon dioxide clearance and arterial CO

conclusionDuring HFOV-VG, ventilator-derived CO WHAT IS KNOWN: • During high-frequency oscillatory ventilation, ventilator-derived indices such as oscillatory tidal volume and DCO2 are commonly used to guide carbon dioxide clearance. • The relationship between ventilator-derived carbon dioxide transport and effective arterial CO2 elimination during HFOV with volume guarantee remains incompletely understood. WHAT IS NEW: • Ventilatory efficiency provides a physiological measure integrating ventilator-derived carbon dioxide transport and arterial CO2 elimination during HFOV with volume guarantee, a relationship that is not routinely evaluated in clinical practice. • Ventilatory efficiency demonstrated modest discrimination for death or moderate-to-severe bronchopulmonary dysplasia, with discrimination improving when combined with markers of respiratory support intensity.

Indexed as

Carbon DioxideHigh-Frequency VentilationRespiratory Distress Syndrome, NewbornBlood Gas AnalysisBronchopulmonary DysplasiaFemaleHumansInfant, NewbornInfant, PrematureMaleCarbon DioxideOscillatory ventilationPreterm infantsVentilatory efficiency

Identifiers

PMID42350871
PMCPMC13303557

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.