ReviewPlanta2026
Nano-enabled RNAi strategies for sustainable citrus protection against viral pathogens.
Review in Planta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionIn conclusion, nanotechnology-assisted RNAi offers a promising and sustainable approach for managing citrus viral diseases through improved dsRNA stability and targeted delivery. Integration of HIGS and SIGS with advanced nanocarriers may enhance antiviral efficiency against diverse citrus pathogens. However, further studies on biosafety, large-scale application, and regulatory approval are essential for successful field implementation. Citrus production is severely constrained by virus and virus-like pathogens that reduce yield fruit quality, and orchard longevity, notably Citrus tristeza virus (CTV), Citrus psorosis virus (CPsV), Citrus vein enation virus (CVEV), Citrus yellow vein-clearing virus (CYVCV) and Citrus leaf blotch virus (CLBV), and emerging or regionally important agents, such as Citrus tatter leaf virus (CTLV), Indian citrus ringspot virus (ICRSV), and citrus yellow mosaic badnavirus (CYMV). Conventional management strategies, including certified planting material, vector suppression, and tolerant rootstock-based approaches, can reduce initial inoculum; however, they often fail to provide durable field-level protection in the presence of efficient vectors and complex virus diversity. RNA interference (RNAi) offers a sequence-specific antiviral approach yet its practical use in citrus is constrained by dsRNA degradation, limited penetration, and poor delivery. Nanotechnology-assisted carriers can improve RNA stability and delivery efficiency through protection and controlled release. This review summarizes citrus viral pathogens, RNA-silencing mechanism and viral suppressors, RNAi strategies (HİGS/SIGS), and nanocarrier design, and outlines key for translation, such as formulation stability, scale-up, and regulation.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.