Evidence map›Paper›PMID 42350840›Full record

ArticlePlanta2026

Species-specific effects of extracellular DNA in Lotus japonicus: local action and drought-related signaling via jasmonate and DREB pathways.

Luigi Migliozzi, Alberta Notte, Fabrizio Cartenì, Stefano Mazzoleni, Vladimir Totev Valkov, Maurizio Chiurazzi

Abstract read
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In one paragraph

Article in Planta, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Luigi MigliozziInstitute of BioSciences and BioResources (CNR), Via P. Castellino 111, 80131, Naples, Italy.
Alberta NotteInstitute of BioSciences and BioResources (CNR), Via P. Castellino 111, 80131, Naples, Italy.
Fabrizio CartenìDepartment of Agricultural Sciences, University of Naples Federico II, P.zza Carlo di Borbone 1, Portici, NA, Italy.
Stefano MazzoleniDepartment of Agricultural Sciences, University of Naples Federico II, P.zza Carlo di Borbone 1, Portici, NA, Italy.
Vladimir Totev ValkovInstitute of BioSciences and BioResources (CNR), Via P. Castellino 111, 80131, Naples, Italy. Vladimirtotev.valkov@cnr.it.
Maurizio ChiurazziInstitute of BioSciences and BioResources (CNR), Via P. Castellino 111, 80131, Naples, Italy. maurizio.chiurazzi@cnr.it.ORCID http://orcid.org/0000-0003-2023-9572

Funding

Agritech, National Research Center CN00000022European Union's Horizon 2020 Research and Innovation Programme 101131175Ministero dell'Istruzione, dell'Università e della Ricerca 2022NW97JX
6 · The paper itself

Abstract

MAIN

conclusionsAnalyses of the effects of extracellular DNA in Lotus japonicus provide novel insights into the spatial dynamics of ex-self-DNA signaling and potential cross-talk with other responsive pathways. The effects of extracellular DNA (exDNA), particularly self-derived DNA, on the signaling pathways involved in plant-soil negative feedback have emerged as significant areas of research in plant biology. Here we characterize the concentration and species-specific effects of exDNA in the model legume Lotus japonicus. We demonstrate progressive, concentration-dependent inhibitory effects of self-derived DNA on plant growth and physiological performance. Using a split-root system, we further investigate the spatial dynamics of self-DNA signaling. Quantitative RT-PCR analysis confirms the involvement of the jasmonic acid (JA) signaling pathway in the response to self-DNA and suggest a role of the dehydration-responsive element-binding (DREB) transcription factors in distinguishing between the effects of self- and non-self exDNA.

Indexed as

CyclopentanesDNA, PlantLotusOxylipinsPlant ProteinsSignal TransductionTranscription FactorsDrought ResistanceDroughtsExtrachromosomal DNAGene Expression Regulation, PlantPlant RootsSpecies SpecificityCyclopentanesDNA, PlantExtrachromosomal DNAjasmonic acidOxylipinsPlant ProteinsTranscription FactorsDrought stressExtracellular DNALocal versus systemicLotus japonicusPlant–soil negative feedbackSplit root

Identifiers

PMID42350840

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.