Evidence map›Paper›PMID 42350784›Full record

ArticleJournal of exposure science & environmental epidemiology2026

The impact of geomagnetic disturbances on mortality from respiratory tract infections in the USA, 2000-2019.

Rim M Harfouch, Paraskevi C Fragkou, Carolina Leticia Zilli Vieira, Petros Koutrakis, Chrysanthi Skevaki

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Article in Journal of exposure science & environmental epidemiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Rim M Harfouch *Institute of Clinical Chemistry and Laboratory Medicine, Institute of Virology, and Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany.
Paraskevi C Fragkou *Center for Public Health Research and Education (CPHRE), Academy of Athens, Athens, Greece.
Carolina Leticia Zilli VieiraDepartment of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA. cazilli@hsph.harvard.edu.
Petros KoutrakisCenter for Public Health Research and Education (CPHRE), Academy of Athens, Athens, Greece.
Chrysanthi SkevakiInstitute of Clinical Chemistry and Laboratory Medicine, Institute of Virology, and Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg-University Mainz, Mainz, Germany. Chrysanthi.Skevaki@unimedizin-mainz.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRespiratory tract infections (RTIs) are a major cause of mortality, particularly among older adults. While air pollution and climate variability are known contributors to RTI risk, the role of solar activity-related short-term geomagnetic disturbances (GMD), remains underexplored.

objectiveThis study investigates the association between GMD, quantified using the 6-month moving average (MA) of the GMD index (Kp), and RTI-related monthly mortality in the United States between 2000 and 2019.

methodsWe analyzed monthly mortality data from 47 contiguous U.S. states using CDC records. RTI-related deaths were identified by ICD-10 codes, and Kp index was used as a GMD exposure metric. We applied generalized estimating equations (GEE) with Poisson regression to estimate relative risks (RRs) and attributable fractions (AFs), adjusting for county-level covariates. Analyses were stratified by sex, age, and U.S. Census regions.

resultsAmong all exposure windows tested (1-12 months), the 6-month MA of the Kp index showed the strongest association. Statistically significant associations were observed in all age groups (65-74, 75-84, ≥85). The RRs per interquartile range (IQR) increase of Kp were 1.14, 1.12, and 1.16 for females, and 1.13, 1.11, and 1.14 for males, respectively. The highest risks were detected in the ≥85 age group: 1.16 (95% CI: 1.14-1.18) for females and 1.14 (95% CI: 1.12-1.16) for males. Geographic variability was also observed, with higher RRs in the West and Midwest regions, though not statistically significant. SIGNIFICANCE: This study provides the first large-scale evidence that GMD may be associated with increased RTI-related mortality in the U.S., particularly among older adults. IMPACT: The findings suggest that solar activity and space weather may influence human health through mechanisms such as immune modulation or circadian disruption. Recognizing GMD as a potential contributor to RTI mortality could inform early warning systems and preventive strategies, especially for vulnerable elderly populations.

Indexed as

GMD Exposure.Kp indexRelative risk (RR)RTI- related MortalitySolar activity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.