Evidence map›Paper›PMID 42350395›Full record

ArticleNature communications2026

Mechanistic insights into chemical exchange during the signal amplification by reversible exchange sensitization of pyruvate.

Charbel D Assaf, Vladimir V Zhivonitko, Amaia Vicario, Alexander A Auer, Simon B Duckett, Jan-Bernd Hövener, Andrey N Pravdivtsev

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Charbel D Assaf *Section Biomedical Imaging (SBMI), Molecular Imaging North Competence Center (MOINCC), Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID http://orcid.org/0000-0003-1968-2112
Vladimir V Zhivonitko *NMR Research Unit, Faculty of Science, University of Oulu, Oulu, Finland. vladimir.zhivonitko@oulu.fi.ORCID http://orcid.org/0000-0003-2919-8690
Amaia VicarioSection Biomedical Imaging (SBMI), Molecular Imaging North Competence Center (MOINCC), Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.
Alexander A AuerMax-Planck-Institut für Kohlenforschung, Mülheim an der Ruhr, Germany.ORCID http://orcid.org/0000-0001-6012-3027
Simon B DuckettCentre for Hyperpolarization in Magnetic Resonance (CHyM), Department of Chemistry, University of York, Heslington, UK.ORCID http://orcid.org/0000-0002-9788-6615
Jan-Bernd HövenerSection Biomedical Imaging (SBMI), Molecular Imaging North Competence Center (MOINCC), Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.ORCID http://orcid.org/0000-0001-7255-7252
Andrey N PravdivtsevSection Biomedical Imaging (SBMI), Molecular Imaging North Competence Center (MOINCC), Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany. andrey.pravdivtsev@rad.uni-kiel.de.ORCID http://orcid.org/0000-0002-8763-617X

Funding

Academy of Finland (Suomen Akatemia) 362959Bundesministerium für Bildung und Forschung (Federal Ministry of Education and Research) 03WIR6208ADeutsche Forschungsgemeinschaft (German Research Foundation) 527469039Deutsche Forschungsgemeinschaft (German Research Foundation) 555951950Deutsche Forschungsgemeinschaft (German Research Foundation) 562203308Deutsche Forschungsgemeinschaft (German Research Foundation) 565789098Deutsche Forschungsgemeinschaft (German Research Foundation) EXC2167/2Deutsche Forschungsgemeinschaft (German Research Foundation) FOR5042Deutsche Forschungsgemeinschaft (German Research Foundation) HO-4602/2-2Deutsche Forschungsgemeinschaft (German Research Foundation) HO-4602/3Deutsche Forschungsgemeinschaft (German Research Foundation) HO-4604/6-1Deutsche Forschungsgemeinschaft (German Research Foundation) HO-4604/8-1Deutsche Forschungsgemeinschaft (German Research Foundation) Inst 257/747-1Deutsche Forschungsgemeinschaft (German Research Foundation) TRR287EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) EP/X023672/1EC | European Regional Development Fund (Europski Fond za Regionalni Razvoj) 122-09-053
6 · The paper itself

Abstract

Signal amplification by reversible exchange (SABRE) is a nuclear spin hyperpolarization technique in which the transient interaction of parahydrogen (pH

Identifiers

PMID42350395
PMCPMC13448611

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.