ArticleInternational journal of laboratory hematology2026
Altitude-Related Laboratory Changes and a Novel Hemoglobin Estimation Model: A Retrospective Analysis in Children and Adults.
Article in International journal of laboratory hematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionHypobaric hypoxia at higher residential altitudes may modify routine laboratory parameters and complicate their interpretation in emergency care. We examined associations between altitude (0-2500 m) and laboratory findings and developed a hemoglobin estimation model.
methodsThis single-center, retrospective cross-sectional study included 2302 patients aged ≥ 1 year admitted to the Emergency Department of Kars Harakani State Hospital on January 1-3 and July 1-3, 2024. Patients were categorized as children (1-17 years) or adults (≥ 18 years). Hematological and biochemical results were retrieved from electronic records. Altitude-laboratory associations were analyzed using correlation and linear regression. A multivariable regression model was constructed to identify determinants of hemoglobin variation.
resultsAmong 2302 admissions, 30.8% were pediatric. Hemoglobin, hematocrit, erythrocyte indices, pO
conclusionResidential altitude was associated with measurable variation in hematological, biochemical, and oxygenation parameters among emergency department patients. Altitude should be considered when interpreting laboratory results in clinical practice. The proposed hemoglobin model integrates altitude and clinical variables to characterize hemoglobin variability within this cohort.
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