Evidence map›Paper›PMID 42350073›Full record

ArticleBMJ open respiratory research2026

Economic impact of initiation of home mechanical ventilation: a budget impact analysis from the Netherlands.

Ries van den Biggelaar, Marieke Duiverman, Anda Hazenberg, J F M van Boven, Karin Vermeulen, Peter J Wijkstra

Abstract read
In one paragraph

Article in BMJ open respiratory research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ries van den BiggelaarDepartment of Pulmonary Diseases/Department of Intensive Care Medicine and Home Mechanical Ventilation, Erasmus Medical Center, Rotterdam, The Netherlands r.vandenbiggelaar@erasmusmc.nl.ORCID http://orcid.org/0000-0001-7144-6876
Marieke DuivermanPulmonary Diseases/Home Mechanical Ventilation, University of Groningen, University Medical Centre Groningen, Groningen, Groningen, The Netherlands.ORCID http://orcid.org/0000-0002-8818-9447
Anda HazenbergDepartment of Home Mechanical Ventialtion, University Medical Center Groningen, Groningen, The Netherlands.
J F M van BovenDepartment of General Practice & Elderly Care Medicine, Groningen Research Institute for Asthma & COPD (GRIAC), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Karin VermeulenDepartment of Epidemiology, University Medical Center Groningen, Groningen, The Netherlands.
Peter J WijkstraPulmonary Diseases, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveIn addition to the already positive outcomes of initiating home mechanical ventilation (HMV) at home, we aimed to explore the economic impact of implementation of initiating HMV at home versus traditional clinical settings, focusing on the Dutch healthcare system.

methodsAn Excel-based cost calculator model was used adhering to International Society of Pharmacoeconomics and Outcomes Research (ISPOR) budget impact analysis guidelines and based on the estimated population of HMV patients from 2023 to 2027 in the Netherlands. We compared home initiation of HMV against inpatient initiation in two scenarios based on patient eligibility and assessed financial impact from both health payer and societal perspectives.

resultsSubstantial cost savings in both scenarios were observed, with significant reductions in hospital admission days and in waiting time among patients who initiated treatment at home. The main scenario (55% of patients initiated at home) indicated savings of €8.4 million for health payers and €10.0 million from a societal perspective over 5 years. The high-uptake scenario (85% of patients initiated at home) showed even greater savings: €13.8 million for health payers and €16.4 million from a societal perspective over 5 years. Tornado diagrams highlighted the low risk of unsuccessful implementation and potential for greater benefits than projected.

conclusionInitiating HMV at home yields substantial budget savings for payers and society in the Netherlands without compromising previously demonstrated clinical outcomes. These findings support broader implementation of home-based HMV initiation and may inform reimbursement reform and wider adoption of home-based HMV initiation.

Indexed as

Health Care CostsHome Care ServicesRespiration, ArtificialBudgetsCost-Benefit AnalysisCost SavingsHumansNetherlandsHealth EconomistNon invasive ventilationRespiratory Muscles

Identifiers

PMID42350073
PMCPMC13311772

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.