Evidence map›Paper›PMID 42349904›Full record

ArticleThe Journal of physiology2026

Evidence that interglomerular inhibition generates non-monotonic concentration-response relationships in mitral/tufted glomeruli in the mouse olfactory bulb.

Lee Min Leong, David Wharton, Narayan Subramanian, Bhargav Karamched, Richard Bertram, Douglas A Storace

Abstract read
In one paragraph

Article in The Journal of physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Lee Min LeongDepartment of Biological Science, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0009-0005-2169-0084
David WhartonDepartment of Mathematics, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0009-0000-5365-0056
Narayan SubramanianDepartment of Biological Science, Florida State University, Tallahassee, Florida, USA.
Bhargav KaramchedDepartment of Mathematics, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0000-0002-6926-7593
Richard BertramDepartment of Mathematics, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0000-0001-8577-2592
Douglas A StoraceDepartment of Biological Science, Florida State University, Tallahassee, Florida, USA.ORCID https://orcid.org/0000-0002-3535-5472

Funding

Chemosensory Training Program (CTP)T32DC000044 · NIDCD · FLORIDA STATE UNIVERSITY · PI DEBRA Ann FADOOL · 1995 to 2026
$5.3M
Understanding functional transformations carried out by the bulbR01DC020519 · NIDCD · FLORIDA STATE UNIVERSITY · PI Douglas Anthony Storace · 2022 to 2026
$1.9M
NIDCD NIH HHS DC000044NIDCD NIH HHS DC020519NIDCD NIH HHS R01 DC020519NIDCD NIH HHS T32 DC000044
6 · The paper itself

Abstract

Animals can recognize an odour as the same odour across a range of concentrations and discriminate between odours in complex environments. Processing within the mouse olfactory bulb (OB) may be involved, yet the underlying mechanisms remain unclear. Each olfactory receptor neuron (ORN) type maps to the OB in olfactory receptor-specific channels called glomeruli, where they connect with the dendrites of mitral and tufted cells (MTCs), which project their axons to the rest of the brain. Modelling this transformation yielded predictions about how two kinds of inhibition, local intraglomerular and lateral interglomerular processing, shape MTC output as a function of concentration changes. We confirmed these predictions using in vivo single and dual-colour two-photon Ca

Indexed as

Neural InhibitionOlfactory BulbOlfactory Receptor NeuronsAnimalsFemaleMaleMiceMice, Inbred C57BLOdorantsSmellcalcium imagingconcentration codingmathematical modelolfactory bulbtransgenic mousetwo‐photon

Identifiers

PMID42349904
PMCPMC13370717

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.