ArticleAustralian veterinary journal2026
Asymptomatic thrombocytopenia in Akitas: a prospective cross-sectional study of platelet characteristics in an Eastern Australian population.
Article in Australian veterinary journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAsymptomatic thrombocytopenia, often associated with macroplatelets, is an important clinical entity that may be misdiagnosed as immune thrombocytopenia due to analyser limitations and low clinician awareness. It is well recognised in Cavalier King Charles Spaniels and other breeds, and has been reported in Akitas in the United States. However, its occurrence and significance in Australian Akitas remain unknown. MATERIALS AND
methodsEighteen clinically healthy Akitas and 11 control dogs from Eastern Australia were evaluated. Blood samples were analysed using an automated haematology analyser, with manual platelet counts and blood film examination performed for comparison. Descriptive and non-parametric statistical analyses were undertaken.
resultsNone of the dogs had clinical signs of bleeding. Thrombocytopenia (<150 × 10
conclusionsAsymptomatic thrombocytopenia was common in Australian Akitas but was not consistently associated with macroplatelets. Discrepancies between automated and manual platelet counts highlight the risk of underestimation by analysers. The condition occurred in both Japanese and American Akita lines without major platelet differences. Awareness and manual confirmation are essential to avoid misdiagnosis and unnecessary treatment.
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