Evidence map›Paper›PMID 42348115›Full record

ArticleCell biochemistry and biophysics2026

Microalgae-Mediated Synthesis of Gold Nanoparticles from Indonesian Chlorella vulgaris InaCC M205 with Potential Anticancer Properties for Biomedical Application.

Nunik Gustini, Debora Christin Purbani, Mega Ferdina Warsito, Riyona Desvy Pratiwi, Diah Radini Noerdjito, Fiddy Semba Prasetiya, Nico Rahman Caesar, Uun Yanuhar, Firli Rahmah Primula Dewi, Arien Dwitrie and 1 more

Abstract read
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Article in Cell biochemistry and biophysics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nunik GustiniResearch Center for Vaccine and Drugs, Research Organization for Health, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Debora Christin PurbaniResearch Center for Biosystematics and Evolution, Research Organization for Life Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Mega Ferdina WarsitoResearch Center for Applied Microbiology, Research Organization for Life Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Riyona Desvy PratiwiResearch Center for Vaccine and Drugs, Research Organization for Health, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Diah Radini NoerdjitoResearch Center for Biosystematics and Evolution, Research Organization for Life Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Fiddy Semba PrasetiyaResearch Center for Biosystematics and Evolution, Research Organization for Life Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Nico Rahman CaesarAquatic Resource Management Study Program, Faculty of Fisheries and Marine Science, Universitas Brawijaya, Malang, Indonesia.
Uun YanuharAquatic Resource Management Study Program, Faculty of Fisheries and Marine Science, Universitas Brawijaya, Malang, Indonesia.
Firli Rahmah Primula DewiBiology Department, Faculty of Science and Technology, Universitas Airlangga, Surabaya, Indonesia.
Arien DwitrieIn Vitro Imaging Laboratory, Genomic Building, Ir. Soekarno Science and Technology Park, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
A'liyatur RosyidahResearch Center for Vaccine and Drugs, Research Organization for Health, National Research and Innovation Agency (BRIN), Bogor, Indonesia. aliyatur.rosyidah@brin.go.id.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sustainable nanomaterial synthesis has emerged as a critical strategy to reduce the environmental burden associated with conventional chemical synthesis method. Microalgae-derived biomolecules offer a promising platform for the green production of metal nanoparticles due to their rich bioactive compounds capable of acting as natural reducing and stabilizing agents. Here, we report the eco-friendly synthesis of gold nanoparticles (AuNPs) using extract of Indonesian microalga Chlorella vulgaris extract. To optimize the synthesis process, the effects of precursor-to-extract ratio, temperature, and incubation time were evaluated. Optimal synthesis of C5-AuNPs was obtained at 37 °C for 20 h with precursor to extract ratio of 6:4, resulting in moderately stable C5-AuNPs characterized by a surface plasmon resonance (SPR) peak at 541 nm. Furthermore, Fourier-transmission infra-red (FT-IR) analysis revealed the involvement of functional groups of C. vulgaris extract in the interaction with Au

Indexed as

Antineoplastic AgentsChlorella vulgarisGoldMetal NanoparticlesMicroalgaeApoptosisGreen Chemistry TechnologyHumansMCF-7 CellsAntineoplastic AgentsGoldAnticancerAuNPsChlorella vulgarisCytotoxicityGreen synthesisMicroalgae extract

Identifiers

PMID42348115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.