ArticleAging clinical and experimental research2026
Associations of length of stay with sarcopenia parameters in geriatric patients: age and sex differences in the oldest old.
Article in Aging clinical and experimental research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Time to pacemaker insertion in older adults: A perspective on mortality and functional outcomes.Aging clinical and experimental research · 2026Article
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8 authors.
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Abstract
backgroundHospital-associated deconditioning is a contributor to secondary sarcopenia, which may be driven by prolonged hospital length of stay (LoS). This study investigated the bidirectional association of LoS and sarcopenia indices (lean soft tissue, muscle strength, physical function) in older inpatients, with a focus on age- and sex-specific differences.
methodsUsing cross-sectional data from the Copenhagen PROTECT study, 1071 older inpatients (aged ≥ 65 years) were included. Appendicular lean soft tissue index (ALSTI), handgrip strength (HGS), gait speed, and 30-second chair stand test (30CST) were assessed within 24 h of admission and sarcopenia was defined per the EWGSOP2 criteria. Linear and logistic regressions examined associations between LoS and sarcopenia indices, stratified by age and sex.
resultsIn patients ≥ 80 years, longer LoS (based on the cohort's median) was associated with lower gait speed and 30CST in both sexes (p < 0.01), and lower HGS in women (p = 0.03). In men < 80 years, longer LoS correlated with lower HGS and 30CST (p < 0.01), with higher odds of sarcopenia (Low ALSTI and low 30CST; OR = 3.14, p = 0.03). Higher 30CST and HGS were consistently associated with shorter LoS, particularly in men ≥ 80 years and women across both age groups.
conclusionsHGS and 30CST are strongly associated with LoS in older inpatients, with more pronounced effects in those ≥ 80 years. Future longitudinal studies and trials are warranted to confirm causality, that may guide rehabilitation strategies to reduce LoS through targeted interventions.
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