Evidence map›Paper›PMID 42347993›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Incidence and progression of ptosis after glaucoma surgery during one year of follow-up.

Nanami Okuzumi, Sotaro Mori, Kana Katakami, Yuto Iwaki, Mari Sakamoto, Yuko Yamada-Nakanishi, Makoto Nakamura

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Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Nanami OkuzumiDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.
Sotaro MoriDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan. smori@med.kobe-u.ac.jp.ORCID http://orcid.org/0000-0003-1991-3232
Kana KatakamiDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.
Yuto IwakiDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.
Mari SakamotoDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.
Yuko Yamada-NakanishiDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.
Makoto NakamuraDepartment of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe city, Hyogo prefecture, 650-0017, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study evaluated the incidence and progression of ptosis during the first year after glaucoma surgery.

methodThis prospective study included patients who underwent initial glaucoma surgery between October 2023 and December 2024. Procedures included microhook ab interno trabeculotomy (µTLO), Preserflo MicroShunt (PMS), trabeculectomy, and Ahmed glaucoma valve (AGV). Margin reflex distance 1 (MRD-1) and MRD-2 were measured preoperatively and at 1, 3, 6, 9 and 12 months using standardised photographs. Ptosis was defined as a decrease in MRD-1 of ≥ 1 mm from baseline. Logistic regression was used to identify factors associated with ptosis. Eyes with absolute MRD-1 ≤ 1 mm were also evaluated at each time point.

resultA total of 167 patients were included: 28 underwent µTLO, 102 PMS, 28 trabeculectomy and 8 AGV implantation. Mean (SD) MRD-1 decreased from 2.5 (1.2) mm preoperatively to 2.1 (1.3) mm at one year. Ptosis occurred in 54 eyes (32.3%). MRD-1 decreased significantly from 1 month through 1 year, whereas MRD-2 showed only a transient decrease at 1 month. No significant MRD-1 reduction occurred after µTLO, whereas significant decreases were observed after filtration surgery. AGV implantation and higher preoperative MRD-1 were associated with ptosis. Eyes with MRD-1 ≤ 1 mm increased over time in the PMS and AGV groups but not after µTLO or trabeculectomy.

conclusionPtosis occurred in about one-third of eyes after glaucoma surgery and progressed up to one year. Filtration surgery was associated with a higher risk of postoperative ptosis.

Indexed as

Glaucoma surgeryMargin reflex distancePreserflo MicroShuntProspective studyPtosisTrabeculectomy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.