Evidence map›Paper›PMID 42347991›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2026

Identification and management of different types of bacillary layer detachment in eyes with rhegmatogenous retinal detachment.

Marzia Affatato, Giuseppe Rapino, Rajeev H Muni, Isabela M Melo, Pasquale Cucciniello, Angela Maria Castelluzzo, Tommaso Rossi, Lucia Ziccardi, Roberto dell'Omo

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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Marzia AffatatoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy.ORCID http://orcid.org/0000-0002-9442-5741
Giuseppe RapinoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy.
Rajeev H MuniDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0003-0465-6472
Isabela M MeloDepartment of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-5371-6286
Pasquale CuccinielloDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy.
Angela Maria CastelluzzoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy.
Tommaso RossiIRCCS, Fondazione Bietti E.T.S., Rome, Italy.
Lucia ZiccardiDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy.ORCID http://orcid.org/0000-0002-5563-1243
Roberto dell'OmoDepartment of Medicine and Health Sciences "Vincenzo Tiberio", University of Molise, Via Francesco De Sanctis 1, Campobasso, 86100, Italy. roberto.dellomo@unimol.it.ORCID http://orcid.org/0000-0002-7663-8874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the preoperative and postoperative features of eyes with fovea-off rhegmatogenous retinal detachment (RRD) and different types of bacillary layer detachment (BALAD), which consists of an intraretinal split within the photoreceptor inner segment myoid zone or formation of a inner lamellar defect at the fovea visible on spectral-domain optical coherence tomography (OCT).

methodsRetrospective cohort study of patients with primary RRD and BALAD who underwent pars plana vitrectomy (PPV). OCT, multicolor images, and logarithm of the minimum angle of resolution (logMAR) best-corrected visual acuities (BCVAs) were obtained preoperatively and at 1, 3, 6, and 12 months after the operation. Three types of BALAD were identified preoperatively on the basis of OCT: cavity, transition and lamellar hole.

resultsAmong the 42 eyes included, 23 were classified as cavity, 6 as transition and 13 as lamellar hole BALAD. All types showed a sharp red round area at the fovea on multicolor images. After standard PPV, additional internal limiting membrane (ILM) peeling was carried out in none eyes with cavity BALAD, in 2 eyes with transition BALAD and in all BALAD-lamellar hole eyes. Post-operatively, no eyes showed evidence of full-thickness macular hole (FTMH). At 12 months post-operatively, external limiting membrane (ELM) and ellipsoid zone (EZ) appeared continuous in 69% (29/42) eyes (24 cavity/transition and 5 BALAD lamellar-hole, P = 0.006) and 54.8% (23/42) eyes (20 cavity/transition and 3 BALAD lamellar-hole, P = 0.004), respectively. Accordingly, BCVA was worse in the eyes with BALAD-lamellar hole than in those with cavity/transition BALAD (0.6 ± 0.4 vs. 0.3 ± 0.2; P = 0.01).

conclusionMulticolor imaging is useful to identify BALAD. Cavity and transition BALAD are likely to not progress to FTMH after retinal reattachment. ILM peeling and cover flap prevented FTMH formation in eyes with BALAD-lamellar hole in this cohort. 12 months postoperatively, restoration rates of integrity of ELM and EZ bands and BCVA scores remained lower in eyes with BALAD-lamellar hole in comparison to those with cavity/transition BALAD.

Indexed as

Bacillary layer detachmentConfocal scanning laser ophthalmoscopeMulticolor imagingOptical coherence tomographyRhegmatogenous retinal detachment.

Identifiers

PMID42347991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.