Evidence map›Paper›PMID 42347900›Full record

ArticleDiscover oncology2026

Sustained improvement in survival for primary ocular adnexal lymphoma from 2005 to 2024 by model-based period analysis.

Jing Zeng, Xianfen Cao, Xi Yin, Qing Zhou, Jun Lyu, Xiangyin Sha

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Article in Discover oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jing ZengOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Xianfen CaoDepartment of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Xi YinOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Qing ZhouDepartment of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.
Jun LyuDepartment of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China. lyujun2020@jnu.edu.cn.
Xiangyin ShaOphthalmic Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China. shaxiangyin@163.com.

Funding

Medical Science and Technology Foundation of Guangdong Province A2023279
6 · The paper itself

Abstract

purposePrimary ocular adnexal lymphoma (POAL) is the most common malignancy affecting para-ocular tissues, making prognosis and survival critical concerns. This study analyzed trends in five-year relative survival rates (RSR) to evaluate survival outcomes.

methodsThis retrospective study included patients diagnosed with POAL from the Surveillance, Epidemiology, and End Results database. Five-year RSR was calculated for the periods 2005-2009, 2010-2014, and 2015-2019. Data were stratified by demographic and clinical characteristics. Model-based period analysis was conducted to assess RSR trends and project RSR for 2020-2024.

resultsThe five-year RSR for POAL patients increased from 96.1% to 99.1% between 2005 and 2019, with projections suggesting continued favorable trends. RSR decreased with advancing age but improved across all age groups; for 2020-2024, RSR was projected to approach 100% for patients aged < 50 and 50-69 years, and 98.3% for those ≥ 70 years. Females consistently showed slightly higher RSR than males. White patients demonstrated steady improvement, while Black patients exhibited a fluctuating trend and other racial groups showed modest increases. Higher RSR was observed in patients with conjunctival involvement, unilateral disease, and mucosal-associated lymphoid tissue (MALT) or follicular lymphoma subtypes.

conclusionSurvival for POAL patients improved between 2005 and 2019. Projected estimates for 2020-2024, while subject to inherent uncertainty, suggest continued favorable outcomes, providing useful prognostic information for clinicians and patients.

Indexed as

Ocular adnexal lymphomaPeriod analysisRelative survival rateSEERSurvival trend

Identifiers

PMID42347900
PMCPMC13558480

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