Evidence map›Paper›PMID 42347760›Full record

ArticleJournal of evidence-based medicine2026

Expert Consensus on the Combined Application of Radiotherapy and Novel Systemic Agents in Breast Cancer Treatment.

Jie Lan, Wenyi Zhou, Qiufan Zheng, Lu Cao, Wenyan Chen, Zhenyu He, Chunling Jiang, Yanchu Li, Wen Xia, Huihua Xiong and 9 more

Abstract readConsensus Statement
In one paragraph

Article in Journal of evidence-based medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Jie LanInstitute of Breast Health Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
Wenyi ZhouDepartment of Radiotherapy for Breast Cancer, Yat-sen Breast Tumor Hospital, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Qiufan ZhengDepartment of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Centre, Guangzhou, China.
Lu CaoDepartment of Radiation Oncology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenyan ChenDepartment of Breast Medicine, Nanchang People's Hospital, Nanchang, China.
Zhenyu HeDepartment of Radiation Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, China.
Chunling JiangDepartment of Radiation Oncology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yanchu LiInstitute of Breast Health Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
Wen XiaDepartment of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Centre, Guangzhou, China.
Huihua XiongDepartment of Oncology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Xiaoli YuDepartment of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Jun ZhangDepartment of Radiation Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Jianli ZhaoBreast Tumor Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Yanxia ZhaoCancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lei LiuInstitute of Breast Health Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
Xin WuInstitute of Breast Health Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.
Shusen WangDepartment of Medical Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Centre, Guangzhou, China.
Xiaobo HuangDepartment of Radiotherapy for Breast Cancer, Yat-sen Breast Tumor Hospital, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.
Jing JingInstitute of Breast Health Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, China.

Funding

Noncommunicable Chronic Diseases-National Science and Technology Major Project 2023ZD0502300 [2023ZD0502301 2023ZD0502302 2023ZD0502303]Sichuan Provincial Engineering Research Center of Intelligent Diagnosis and Treatment of Breast DiseasesSichuan Science and Technology Program 2025ZDZX0012
6 · The paper itself

Abstract

The rapid advancement of radiotherapy techniques and systemic anticancer agents has created unprecedented opportunities to improve outcomes for breast cancer patients, while also introducing new challenges related to optimal integration and safety. This consensus, convened by the Breast Cancer Committee of the Chinese Anti-Cancer Association and Chinese Society of Clinical Oncology Breast Cancer Committee, systematically evaluated available literature through November 2025 and employed Delphi methodology to generate evidence-based recommendations for combining radiotherapy with immune checkpoint inhibitors, targeted therapies, antibody-drug conjugates and endocrine agents across disease stages. This work aims to guide clinicians toward safer and more effective integration of radiotherapy with contemporary systemic treatments, promote consistency in clinical practice, and identify priority directions for future research to refine precision radiotherapy and systemic therapy combinations in breast cancer.

Indexed as

Antineoplastic AgentsBreast NeoplasmsCombined Modality TherapyFemaleHumansImmune Checkpoint InhibitorsImmunoconjugatesAntineoplastic AgentsImmune Checkpoint InhibitorsImmunoconjugatesbreast cancercombination treatmentradiotherapysystemic agents

Identifiers

PMID42347760
PMCPMC13320105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.