Evidence map›Paper›PMID 42347708›Full record

ArticleJournal of diabetes investigation2026

Adaptive islet biology and comprehensive incretin physiology: Emerging perspectives from Asia and Europe.

Takaaki Murakami, Daniela Nasteska, David J Hodson, Yuji Yamazaki, Daisuke Yabe, Yutaka Seino

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of diabetes investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Takaaki MurakamiDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0003-3844-1138
Daniela NasteskaOxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Centre, Bukhman Centre for Research Excellence in Type 1 Diabetes, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
David J HodsonOxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), NIHR Oxford Biomedical Research Centre, Bukhman Centre for Research Excellence in Type 1 Diabetes, Churchill Hospital, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Yuji YamazakiKansai Electric Power Hospital, Osaka, Japan.ORCID https://orcid.org/0009-0007-5876-8695
Daisuke YabeDepartment of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0002-5334-7687
Yutaka SeinoKansai Electric Power Hospital, Osaka, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adaptive islet biology and incretin physiology provide a framework linking diverse diabetes phenotypes, with advances in β-cell stress adaptation, intra-islet communication, receptor-resolved biology, and β-cell mass imaging. By integrating clinical perspectives from Asia and Europe with multiscale islet-cell biology, these insights may support mechanism-based and more targeted therapeutic approaches.

Indexed as

Adaptation, PhysiologicalDiabetes Mellitus, Type 2IncretinsInsulin-Secreting CellsIslets of LangerhansAnimalsAsiaEuropeHumansIncretins

Identifiers

PMID42347708
PMCPMC13398969

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.