Evidence map›Paper›PMID 42347666›Full record

ArticleVaccines2026

Immunogenicity of a Recombinant Multi-Epitope Vaccine Incorporating GRA14, SAG1, and GRA1 Antigens of

Abdulrahman M Sheikh, Wong Weng Kin, Robaiza Zakaria, Ahmad A Alshehri, Mohammed Dauda Goni, Abdulrazzag Abdulaziz Othman, Zakeya Al Rasbi, Zeehaida Mohamed, Khalid Hajissa

Abstract read
In one paragraph

Article in Vaccines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abdulrahman M SheikhDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0002-7448-9094
Wong Weng KinSchool of Health Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0003-2189-638X
Robaiza ZakariaDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Ahmad A AlshehriDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University, Najran P.O. Box 1988, Saudi Arabia.ORCID 0000-0002-3143-3023
Mohammed Dauda GoniFaculty of Veterinary Medicine, Universiti Malaysia Kelantan, Pengkalan Chepa, Kota Baru 16100, Kelantan, Malaysia.ORCID 0000-0003-1301-5351
Abdulrazzag Abdulaziz OthmanDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Riyadh 11961, Saudi Arabia.ORCID 0000-0003-4233-1978
Zakeya Al RasbiDepartment of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0001-9909-8658
Zeehaida MohamedDepartment of Medical Microbiology & Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Khalid HajissaDepartment of Medical Microbiology and Immunology, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain P.O. Box 15551, United Arab Emirates.ORCID 0000-0002-1725-6702

Funding

University of Science Malaysia 304/PPSP/6315419.
6 · The paper itself

Abstract

backgroundThe high incidence and severe health threat of

methodsUsing bioinformatics approach, the USM.TOXOII was designed and evaluated. The encoding gene (471 bp) was then constructed and cloned into the pET-30a (+) plasmid before being transformed into

resultsThe USM.TOXOII protein (17.27 kDa) was soluble and contained a His tag protein. Immunization of BALB/c mice with USM.TOXOII significantly elevated serum levels of total IgG, IgG1, and IgG2a (

conclusionsCollectively, these findings indicate that USM.TOXOII possesses immunogenic potential and is capable of inducing both humoral and cellular immune responses in BALB/c mice. Future challenge studies with live

Indexed as

immunogenicityimmunoinformaticsmulti-epitopeToxoplasma gondiivaccine

Identifiers

PMID42347666
PMCPMC13307803

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.