Evidence map›Paper›PMID 42347527›Full record

ArticleToxins2026

Chemical, Biological, and Ecological Evidence for Aerobic Deoxynivalenol Detoxification in Agronomic Soil-Derived Bacterial Communities.

Natalia Martínez-Reyes, Rosa E Cardoza, Estela Melcón-Fernández, Rafael Balaña-Fouce, Lea Brückner, Rocío Montes-Ruiz, Benedikt Cramer, Hans-Ulrich Humpf, Pedro A Casquero, Santiago Gutiérrez

Abstract read
In one paragraph

Article in Toxins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Natalia Martínez-ReyesGrupo Universitario de Investigación en Ingeniería y Agricultura Sostenible (GUIIAS), Área de Microbiología, Universidad de León, 24400 Ponferrada, Spain.ORCID 0000-0001-6560-417X
Rosa E CardozaGrupo Universitario de Investigación en Ingeniería y Agricultura Sostenible (GUIIAS), Área de Microbiología, Universidad de León, 24400 Ponferrada, Spain.ORCID 0000-0002-6589-0062
Estela Melcón-FernándezDepartamento de Ciencias Biomédicas, Facultad de Veterinaria, Universidad de León, 24071 León, Spain.ORCID 0000-0002-9663-060X
Rafael Balaña-FouceDepartamento de Ciencias Biomédicas, Facultad de Veterinaria, Universidad de León, 24071 León, Spain.ORCID 0000-0003-0418-6116
Lea BrücknerInstitute of Food Chemistry, University of Münster, 48149 Münster, Germany.
Rocío Montes-RuizGrupo Universitario de Investigación en Ingeniería y Agricultura Sostenible (GUIIAS), Instituto de Medio Ambiente, Recursos Naturales y Biodiversidad, Universidad de León, Avenida Portugal 41, 24071 León, Spain.
Benedikt CramerInstitute of Food Chemistry, University of Münster, 48149 Münster, Germany.ORCID 0000-0001-7632-8676
Hans-Ulrich HumpfInstitute of Food Chemistry, University of Münster, 48149 Münster, Germany.ORCID 0000-0003-3296-3058
Pedro A CasqueroGrupo Universitario de Investigación en Ingeniería y Agricultura Sostenible (GUIIAS), Instituto de Medio Ambiente, Recursos Naturales y Biodiversidad, Universidad de León, Avenida Portugal 41, 24071 León, Spain.ORCID 0000-0002-4432-9794
Santiago GutiérrezGrupo Universitario de Investigación en Ingeniería y Agricultura Sostenible (GUIIAS), Área de Microbiología, Universidad de León, 24400 Ponferrada, Spain.ORCID 0000-0001-6659-1390

Funding

Agencia Estatal de Investigación PID2021-123874O-I00Ministerio de Ciencia, Innovación y Universidades PID2021-123874O-I00
6 · The paper itself

Abstract

Deoxynivalenol (DON) is a prevalent trichothecene mycotoxin in cereals that poses food and feed safety risks while causing important economic losses. Microbial biotransformation offers a selective, mild strategy for DON detoxification. Here, we screened aerobic soil-derived bacterial communities from diverse agricultural environments, using DON as the sole carbon source for this mycotoxin depletion. More than half of the tested enrichment samples showed a reduced DON signal, as observed by HPLC-UV. To assess the biological relevance, culture extracts were tested for cytotoxicity in HepG2 cells. Z13, a soil sample that depleted DON but produced no other detectable metabolites, showed reduced cytotoxicity, comparable to the negative control. In contrast, samples that depleted DON but produced 3-keto-DON remained toxic. High-resolution LC-MS analysis indicated the formation of metabolites putatively identified as 3-keto-DON in enrichment cultures and 3-epi-DON in a

Indexed as

BacteriaMicrobiotaSoil MicrobiologyTrichothecenesAerobiosisBiotransformationCell SurvivalHep G2 CellsHumansInactivation, MetabolicRNA, Ribosomal, 16SdeoxynivalenolRNA, Ribosomal, 16STrichothecenesbiotransformationdeoxynivalenoldetoxificationmass spectrometrymycotoxinssoil bacteria

Identifiers

PMID42347527
PMCPMC13307919

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.