ArticleSports (Basel, Switzerland)2026
Acute Moderate-Dose β-Alanine Improves Exercise Efficiency via Bicarbonate-Related Mechanisms During a Cycling Time Trial.
Article in Sports (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundResearch on the acute effects of β-alanine supplementation has primarily focused on performance outcomes, with limited attention to the underlying physiological mechanisms. This study aimed to investigate the acute effects of two β-alanine doses on performance, mechanical output, and acid-base balance during a 10 min cycling time trial (10'-TT), and to explore the relationship between buffering-related variables and performance.
methodsEighty-five recreational cyclists performed a 10'-TT under indoor conditions before (control) and following the acute ingestion of β-alanine (moderate-dose β-alanine 10 g-BAM; high-dose β-alanine 20 g-BAH) or placebo (PLA), with each condition tested on separate days. Data were analyzed using two-way repeated-measures ANOVA and correlation analyses.
resultsNo significant differences were observed in performance variables (distance, speed, cadence, or heart rate;
conclusionsAcute β-alanine supplementation did not improve performance outcomes but may alter buffering-related physiological responses associated with reduced mechanical work during high-intensity cycling exercise. These findings highlight the relevance of buffering-related mechanisms, particularly bicarbonate dynamics, in modulating the mechanical cost (work performed relative to performance achieved) of high-intensity exercise.
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