Evidence map›Paper›PMID 42347415›Full record

ArticleToxics2026

Neonatal Exposure to Di(2-ethylhexyl) Phthalate Is Associated with Lung Injury in a Rat Model of Chronic Lung Disease of Prematurity.

Shahana Perveen, Li Lou, Sohini Alim, Abigail Akselrod, Chunfang Zhao, Namita Sen, Clifford S Deutschman, Annemarie Stroustrup

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shahana PerveenNorthwell Health, New Hyde Park, NY 11040, USA.ORCID 0000-0001-5750-1787
Li LouNorthwell Health, New Hyde Park, NY 11040, USA.
Sohini AlimNorthwell Health, New Hyde Park, NY 11040, USA.ORCID 0009-0002-1596-9925
Abigail AkselrodNorthwell Health, New Hyde Park, NY 11040, USA.ORCID 0009-0002-5306-1029
Chunfang ZhaoNorthwell Health, New Hyde Park, NY 11040, USA.
Namita SenNorthwell Health, New Hyde Park, NY 11040, USA.
Clifford S DeutschmanNorthwell Health, New Hyde Park, NY 11040, USA.
Annemarie StroustrupNorthwell Health, New Hyde Park, NY 11040, USA.ORCID 0000-0002-5667-6195

Funding

Phthalate Exposure and Mechanisms of Action in the Neonatal Intensive Care UnitR01ES034018 · NIEHS · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI Annemarie Stroustrup · 2023 to 2026
$2.8M
NIEHS NIH HHS R01ES034018
6 · The paper itself

Abstract

Chronic lung disease of prematurity (CLD) is a common complication of preterm birth with a complex pathology. Recent epidemiologic studies have identified a link between neonatal exposure to di(2-ethylhexyl) phthalate (DEHP), frequently used in medical equipment, and the development of CLD. We hypothesize that DEHP exposure in the early neonatal period contributes to lung injury in newborn rats. Newborn rat pups were raised in one of the following environments: room air (RA), RA + DEHP, hyperoxia (60% oxygen), and hyperoxia + DEHP. Ambient DEHP was inhaled at a dose of 25 mg/m

Indexed as

animal modelbronchopulmonary dysplasiachronic lung diseaseenvironmental toxinlung injuryphthalatesprematurity

Identifiers

PMID42347415
PMCPMC13307714

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.