Combined Toxicity of Ofloxacin and Sulfamethoxazole at Environmentally Relevant Concentrations in Mosquitofish: Histopathological Damage, Oxidative Stress, and Gut Microbiota Alterations.

Xu Ding, Xin Li, Haojie Liu, Zhong Li, Yangchun Xia, Yanpeng Liang, Honghu Zeng, Xiaohong Song

Abstract read

In one paragraph

Article in Toxics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xu DingGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.

Xin LiGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.

Haojie LiuGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.

Zhong LiUniversity Engineering Research Center of Watershed Protection and Green Development, Guilin University of Technology, Guilin 541006, China.

Yangchun XiaKey Laboratory of Carbon Emission and Pollutant Collaborative Control, Education Department of Guangxi Zhuang Autonomous Region, Guilin University of Technology, Guilin 541006, China.

Yanpeng LiangGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.

Honghu ZengGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.

Xiaohong SongGuangxi Key Laboratory of Environmental Pollution Control Theory and Technology, Guilin University of Technology, Guilin 541006, China.ORCID 0000-0002-2583-1340

Funding

Guangxi Science and Technology Department 2026GXNSFAA00641047Guangxi Science and Technology Department Guike AD25069074

6 · The paper itself

Abstract

Ofloxacin (OFL) and sulfamethoxazole (SMX) are common co-occurring antibiotic contaminants in aquatic environments, yet their long-term combined toxicity to freshwater fish remains poorly elucidated. In this study, adult mosquitofish (

Indexed as

gut microbiotahistopathologyofloxacinoxidative stresssulfamethoxazole

Identifiers

PMID42347355

DOI10.3390/toxics14060457

PMCPMC13306796

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.