Evidence map›Paper›PMID 42347252›Full record

ArticlePathogens (Basel, Switzerland)2026

Development of Peptide Entry Inhibitors Targeting the Endosomal Receptor NPC1 Binding Site of

Leah Liu Wang, Kendra Alfson, J J Patten, Marc E Mattix, Yenny Goez-Gazi, Sean N Avedissian, Robert A Davey, Ricardo Carrion, Shi-Hua Xiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Leah Liu WangSchool of Veterinary Medicine and Biomedical Sciences, Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.
Kendra AlfsonTexas Biomedical Research Institute, 8715 W. Military Drive, San Antonio, TX 78227, USA.ORCID 0000-0001-6031-5360
J J PattenNational Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02115, USA.ORCID 0000-0002-9770-7525
Marc E MattixNonclinical Pathology Services, LLC, 5920 Clubhouse Pointe Dr., Medina, OH 44256, USA.
Yenny Goez-GaziTexas Biomedical Research Institute, 8715 W. Military Drive, San Antonio, TX 78227, USA.
Sean N AvedissianCollege of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-0935-6455
Robert A DaveyNational Emerging Infectious Diseases Laboratories, Boston University, Boston, MA 02115, USA.ORCID 0000-0001-9168-2892
Ricardo CarrionTexas Biomedical Research Institute, 8715 W. Military Drive, San Antonio, TX 78227, USA.ORCID 0000-0001-7046-7683
Shi-Hua XiangSchool of Veterinary Medicine and Biomedical Sciences, Nebraska Center for Virology, University of Nebraska-Lincoln, Lincoln, NE 68588, USA.ORCID 0000-0002-5656-5698

Funding

National Institute of Allergy and Infectious Diseases 1R21AI51483
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsEbolavirusPeptidesVirus InternalizationAnimalsBinding SitesDisease Models, AnimalEndosomesHemorrhagic Fever, EbolaHumansIntracellular Signaling Peptides and ProteinsMiceNiemann-Pick C1 ProteinProtein BindingAntiviral AgentsIntracellular Signaling Peptides and ProteinsNiemann-Pick C1 ProteinNPC1 protein, humanPeptidesEbola virus disease (EVD)entry inhibitorNiemann–Pick C1 (NPC1)Orthoebolavirus bundibugyoense (BDBV)Orthoebolavirus zairense (EBOV)peptidereceptor-binding site (RBS)

Identifiers

PMID42347252
PMCPMC13304712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.