Evidence map›Paper›PMID 42346795›Full record

ArticleMarine drugs2026

Low-Level Domoic Acid Exposure Induces Age-like Cardiomyopathy in Young Adult and Aged Mice.

Sophia Liu, Alicia Hendrix, James MacDonald, Theo Bammler, Kathi A Lefebvre, David J Marcinek

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sophia LiuDepartment of Radiology, University of Washington Medical School, Seattle, WA 98109, USA.
Alicia HendrixPacific Islands Fish and Wildlife Office, U.S. Fish and Wildlife Service, Honolulu, HI 96850, USA.
James MacDonaldDepartment of Environmental and Occupational Health, University of Washington, Seattle, WA 98109, USA.
Theo BammlerDepartment of Environmental and Occupational Health, University of Washington, Seattle, WA 98109, USA.
Kathi A LefebvreEnvironmental Chemistry Program, Environmental and Fisheries Science Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, Seattle, WA 98112, USA.ORCID 0000-0002-1036-3740
David J MarcinekDepartment of Radiology, University of Washington Medical School, Seattle, WA 98109, USA.ORCID 0000-0001-5187-2149

Funding

University of Washington Nathan Shock Center of Excellence in the Basic Biology of AgingP30AG013280 · NIA · UNIVERSITY OF WASHINGTON · PI Su-In Lee · 1995 to 2026
$27.1M
Mechanisms underlying reversal of cardiac aging by urolithin a treatmentR01AG081395 · NIA · UNIVERSITY OF WASHINGTON · PI David J. Marcinek, MICHAEL REGNIER · 2024 to 2026
$3.2M
Increased Risk of Chronic Disease Due to Domoic Acid Exposure with AgeR01ES030319 · NIEHS · UNIVERSITY OF WASHINGTON · PI MARCINEK, DAVID J. · 2018 to 2022
$652k
NIA NIH HHS P30 AG013280NIA NIH HHS R01 AG081395NIEHS NIH HHS R01ES030319U.S. National Science Foundation OCE1839041
6 · The paper itself

Abstract

Domoic acid (DA) is a well-known seafood toxin produced by some species of marine phytoplankton in the genus

Indexed as

AgingCardiomyopathiesKainic AcidMarine ToxinsAge FactorsAnimalsMaleMicedomoic acidKainic AcidMarine Toxinschronicexcitotoxicityharmful algal bloom (HAB)seafood toxinssubacute exposure

Identifiers

PMID42346795
PMCPMC13302463

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.