Evidence map›Paper›PMID 42346791›Full record

ArticleMarine drugs2026

New Bicyclic Sesquiterpene and Labdane Diterpenes from the Culture Extract of the Sea Grass-Derived Fungus

Diana I C Pinho, Tida Dethoup, Ruchiluk Rattarom, Emília Sousa, Salar Hafez-Ghoran, Artur M S Silva, Luís Gales, Anake Kijjoa

Abstract read
In one paragraph

Article in Marine drugs, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Diana I C PinhoSchool of Medicine and Biomedical Sciences Abel Salazar (ICBAS) and CIIMAR, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0009-0004-5433-0707
Tida DethoupDepartment of Plant Pathology, Faculty of Agriculture, Kasetsart University, Bangkok 10240, Maha Sarakham, Thailand.ORCID 0000-0002-9079-3010
Ruchiluk RattaromPharmaceutical Chemistry and Natural Product Research Unit, Faculty of Pharmacy, Mahasarakham University, Kantharawichai 44150, Maha Sarakham, Thailand.ORCID 0000-0002-3477-0121
Emília SousaLaboratório de Química Orgânica e Farmacêutica, Departamento de Ciências Químicas, Faculdade de Farmácia, Universidade do Porto and CIIMAR, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-5397-4672
Salar Hafez-GhoranLaboratory for Functional Foods and Human Health, Center for Excellence in Post-Harvest Technologies, North Carolina Agricultural and Technical State University, North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC 28081, USA.ORCID 0000-0001-5495-5556
Artur M S SilvaDepartamento de Química & QOPNA, Universidade de Aveiro, 3810-193 Aveiro, Portugal.ORCID 0000-0003-2861-8286
Luís GalesSchool of Medicine and Biomedical Sciences Abel Salazar (ICBAS) and Instituto de Biologia Molecular e Celular (i3S-IBMC), Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-8352-6539
Anake KijjoaSchool of Medicine and Biomedical Sciences Abel Salazar (ICBAS) and CIIMAR, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.ORCID 0000-0002-3321-1061

Funding

Fundação para a Ciência e Tecnologia UIDB/04423/2020 and UIDP/04423/2020.
6 · The paper itself

Abstract

An unreported bicyclic sesquiterpene acid, verruculosic acid (

Indexed as

DiterpenesPenicilliumPoaceaeSesquiterpenesAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsCrystallography, X-RayMacrophagesMiceMolecular StructureNitric OxideRAW 264.7 CellsAnti-Bacterial AgentsAnti-Inflammatory AgentsDiterpeneslabdaneNitric OxideSesquiterpeneslabdane diterpenesmarine-derived fungusnitric oxide inhibitory activitynor-seco-labdane diterpenePenicillium verruculosum KUFA1509RAW264.7 macrophagessea grassverruculosic acid

Identifiers

PMID42346791
PMCPMC13301828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.