Evidence map›Paper›PMID 42346668›Full record

ArticleJournal of functional biomaterials2026

The Influence of Mechanical and Microstructural Characteristics on the Durability of a Femoral Implant Made of Different Alloys.

Ivan Panfilov, Evgeniy Sadyrin, Andrey Nikolaev, Pavel Antipov, Andrey Vasiliev, Ilya Vilkovyskiy, Andrei Pantiulin, Oxana Ananova, Besarion Meskhi

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ivan PanfilovDepartment of Theoretical and Applied Mechanics, Agribusiness Faculty, Don State Technical University, 1 Gagarin Square, 344003 Rostov-on-Don, Russia.ORCID 0000-0002-0955-0282
Evgeniy SadyrinDepartment of Theoretical and Applied Mechanics, Agribusiness Faculty, Don State Technical University, 1 Gagarin Square, 344003 Rostov-on-Don, Russia.
Andrey NikolaevScientific and Educational Center "Materials", Don State Technical University, 1 Gagarin Square, 344003 Rostov-on-Don, Russia.
Pavel AntipovScientific and Educational Center "Materials", Don State Technical University, 1 Gagarin Square, 344003 Rostov-on-Don, Russia.ORCID 0009-0009-8752-8572
Andrey VasilievScientific and Educational Center "Materials", Don State Technical University, 1 Gagarin Square, 344003 Rostov-on-Don, Russia.
Ilya VilkovyskiyDepartment of Veterinary Medicine, RUDN University, 6 Miklukho-Maklaya St., 117198 Moscow, Russia.
Andrei PantiulinDepartment of Veterinary Medicine, RUDN University, 6 Miklukho-Maklaya St., 117198 Moscow, Russia.ORCID 0009-0003-5376-0986
Oxana AnanovaDepartment of Marketing and Engineering Economics, Faculty of Innovative Business and Management, Don State Technical University, 344003 Rostov-on-Don, Russia.ORCID 0000-0003-0645-3097
Besarion MeskhiDepartment of Life Safety and Environmental Protection, Faculty of Life Safety and Environmental Engineering, Don State Technical University, Gagarin, 1, 344003 Rostov-on-Don, Russia.ORCID 0000-0003-3497-3102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The long-term success of orthopedic implants is fundamentally dependent on the synergy between mechanical performance and biological integration. Thus, a comprehensive investigation of both mechanical characteristics and microstructural parameters is essential for the development of reliable implant systems in hip arthroplasty, both in human medicine and veterinary practice. The present study provides a detailed analysis of the mechanical properties, microstructure, and chemical composition of a Ti-6Al-4V-based femoral implant using nanoindentation, scanning electron and optical microscopy, and energy-dispersive X-ray spectroscopy. Then, using finite element analysis, the influence of Young's modulus on the stress-strain state of the endoprosthesis was evaluated. Dynamic loading conditions were considered by analyzing an impact on a cantilever beam, simulating an animal's jump onto a supporting limb. For reliable numerical simulation, the model geometry was constructed utilizing computed X-ray microtomography. The numerical simulations were performed for three material cases: reference Ti-6Al-4V, experimentally characterized Ti-6Al-4V (with properties determined by nanoindentation), and CoCrMo alloy, which is also widely used in endoprosthetic applications. The influence of the founded mechanical characteristics on the stress-strain state of the prostheses was assessed. In particular, the results indicate that under dynamic loading conditions, the load-bearing capacity of CoCrMo is lower by approximately 30% and 21% compared to the reference and experimentally characterized Ti-6Al-4V, respectively.

Indexed as

chemical compositiondynamic loadingfemoral implantfinite element analysismicrostructuremicrotomographynanoindentationreverse engineeringstress concentratorstitanium alloy

Identifiers

PMID42346668
PMCPMC13301481

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.