Evidence map›Paper›PMID 42346662›Full record

ArticleJournal of functional biomaterials2026

Acid-Induced Surface Degradation of Metallic Biomaterials: Alloy-Dependent Behavior and Implications for Surface Functionality.

Réka Niklai, Péter Szabó, Judit Kopniczky, Tímea Dergez, Béla Kolarovszki, Orsolya Kada, Ákos Nagy, Kinga Turzó, Dorottya Frank

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Réka NiklaiDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.
Péter SzabóInstitute of Geography and Earth Sciences, University of Pécs, Ifjúság Útja 6., H-7624 Pécs, Hungary.
Judit KopniczkyDepartment of Optics and Quantum Electronics, University of Szeged, Dóm Tér 9., H-6720 Szeged, Hungary.
Tímea DergezInstitute of Bioanalysis, Medical School, University of Pécs, Honvéd u. 1., H-7624 Pécs, Hungary.ORCID 0009-0003-1096-775X
Béla KolarovszkiDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.ORCID 0009-0002-9122-7974
Orsolya KadaDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.
Ákos NagyDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.
Kinga TurzóDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.ORCID 0000-0003-4133-3998
Dorottya FrankDental School, Faculty of Medicine, University of Pécs, Tüzér u. 1., H-7633 Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metallic biomaterials are frequently exposed to chemically aggressive environments that may compromise surface integrity and corrosion resistance. Acidic media containing organic acids represent a relevant challenge for metallic systems, as they can destabilize passive oxide layers and promote surface degradation processes. The present in vitro study investigated acid-induced surface alterations in four commercially relevant orthodontic alloys-nickel-titanium (NiTi), copper-nickel-titanium (CuNiTi), titanium-molybdenum alloy (TMA), and stainless steel-as representative metallic biomaterials. Specimens were exposed to two commercially available acidic beverages with distinct pH conditions, followed by analysis of surface morphology, roughness, and elemental composition using atomic force microscopy (AFM), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDS). The results demonstrated pronounced alloy-dependent differences in degradation behavior. Stainless steel and TMAs exhibited significant increases in surface roughness and morphological alterations, whereas NiTi-based alloys showed comparatively stable surface characteristics. Elemental analysis revealed material-specific compositional variations, suggesting selective surface modification processes under acidic exposure. These differences can be attributed to variations in alloy composition, microstructure, and the stability of passive oxide layers, which collectively govern corrosion resistance in metallic systems. The findings provide insight into acid-induced degradation mechanisms in metallic biomaterials and highlight the importance of material-dependent corrosion behavior under chemically aggressive conditions. These observations may have implications for surface-mediated biological responses and long-term functional performance of metallic biomaterials.

Indexed as

biocompatibilitycorrosionion releasemetallic biomaterialspassive oxide layersurface degradationsurface functionalitysurface roughness

Identifiers

PMID42346662
PMCPMC13301228

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.