Evidence map›Paper›PMID 42346589›Full record

ArticleJournal of personalized medicine2026

Genetic Determinants of T-Cell Homeostasis in Critical Illness: An Exploratory Analysis of Immune Gene Variants and TREC Dynamics.

Alesya S Gracheva, Darya A Kashatnikova, Maryam B Khadzhieva, Vladislav E Zakharchenko, Tatyana N Krylova, Artem N Kuzovlev, Lyubov E Salnikova

Abstract read
In one paragraph

Article in Journal of personalized medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alesya S GrachevaVavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0003-1361-6085
Darya A KashatnikovaVavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0003-3051-6756
Maryam B KhadzhievaFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.ORCID 0000-0002-8980-4851
Vladislav E ZakharchenkoFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.ORCID 0000-0003-4873-8007
Tatyana N KrylovaFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.
Artem N KuzovlevFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, 107031 Moscow, Russia.ORCID 0000-0002-5930-0118
Lyubov E SalnikovaVavilov Institute of General Genetics, Russian Academy of Sciences, 119333 Moscow, Russia.ORCID 0000-0002-9671-335X

Funding

The Ministry of Education and Science of the Russian Federation FGWS-2025-0008; 125091010190-9
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chronic critical illness (CCI)immune genesqualifying genetic variantsT-cell receptor excision circles (TREC) trajectorytraumatic brain injury (TBI)whole-exome sequencing (WES)

Identifiers

PMID42346589
PMCPMC13300954

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.