Evidence map›Paper›PMID 42346505›Full record

ArticleJournal of cardiovascular development and disease2026

QRS-Corrected Prediction of the Diastolic Rest Period for Coronary CT Angiography in Patients with Complete Left Bundle Branch Block.

Tsubasa Morioka, Shingo Kato, Kouta Mitsutake, Hidenao Yanagisawa, Toshiharu Izumi, Tomokazu Sakano, Eiji Ishikawa, Hiroyuki Kamide, Daisuke Utsunomiya

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Article in Journal of cardiovascular development and disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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9 authors.

Tsubasa MoriokaDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Shingo KatoDepartment of Diagnostic Radiology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.ORCID 0000-0002-7545-0669
Kouta MitsutakeDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Hidenao YanagisawaDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Toshiharu IzumiDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Tomokazu SakanoDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.
Eiji IshikawaDepartment of Radiology, Yokohama City University Hospital, Yokohama 236-0004, Japan.ORCID 0009-0006-2436-3203
Hiroyuki KamideDepartment of Diagnostic Radiology, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Daisuke UtsunomiyaDepartment of Diagnostic Radiology, Yokohama City University Graduate School of Medicine, Yokohama 236-0004, Japan.ORCID 0000-0002-1723-1724

Funding

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6 · The paper itself

Abstract

backgroundOptimal phase selection in coronary computed tomography angiography (CCTA) is crucial. While the mid-diastolic slow-filling (SF) phase is typically predicted using a conventional formula based on heart rate and atrioventricular conduction time, its validity in complete left bundle branch block (CLBBB)-where pronounced QRS prolongation induces severe mechanical dyssynchrony-remains unclear. We evaluated the impact of bundle branch block on cardiac-phase selection and validated a QRS-corrected predictive model.

methodsWe retrospectively analyzed 94 patients (sinus rhythm,

resultsIn CLBBB patients, the conventional formula critically overestimated SF by an average of 37.9 ms (RMSE 42.5 ms). Reconstructing simple and multivariate regression models exclusively for the CLBBB group yielded coefficients remarkably similar to the conventional formula, indicating that the fundamental physiological dependency on RR and PQ intervals remains intact despite the bundle branch block. Crucially, the simple proposed QRS-corrected formula successfully eliminated the overestimation bias (mean error -6.9 ms;

conclusionsA completely new predictive regression model is unnecessary for CLBBB patients. Simply incorporating a theoretical subtraction of pathological QRS prolongation optimally corrects the diastolic resting phase.

Indexed as

bundle branch blockcardiac phasecoronary CT angiographyleft bundle branch blockQRS durationslow filling

Identifiers

PMID42346505
PMCPMC13302584

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