Evidence map›Paper›PMID 42346422›Full record

ArticleJournal of xenobiotics2026

Phenotypic Subacute Toxicity Assessment of Intranasally Administered Larixyl Acetate: Implications for Potential Airway Applications.

Zaina Kalaji, Ibrahim Hachim, Marwa Almazrouei, Hanaa Habbal, Vidya Bijosh Mohan, Mohammad G Mohammad, Rifat Hamoudi, Rabih Halwani

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of xenobiotics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zaina KalajiResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0001-7802-1790
Ibrahim HachimResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0001-6438-9455
Marwa AlmazroueiResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Hanaa HabbalResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Vidya Bijosh MohanResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.
Mohammad G MohammadResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-6775-1955
Rifat HamoudiResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.ORCID 0000-0002-1402-0868
Rabih HalwaniResearch Institute of Medical and Health Sciences, College of Medicine, University of Sharjah, Sharjah P.O. Box 27272, United Arab Emirates.

Funding

Ongoing Research Funding program - Research Chairs ORF-RC-2026-0500
6 · The paper itself

Abstract

Larixyl acetate, a primary component of Larch turpentine, is a naturally occurring compound with a broad spectrum of medicinal properties, including anti-inflammatory effects. It is a potent and selective inhibitor of TRPC6, a widely expressed Ca

Indexed as

intranasal deliveryLarixyl acetateOECD Test Guideline 412subacute toxicity

Identifiers

PMID42346422
PMCPMC13301338

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.